Chantal A Lebbink
Chantal A Lebbink
Wilhelmina Children’s Hospital and Princess Máxima Center, Utrecht, The Netherlands
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Thera P Links
Thera P Links
Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
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Agnieszka Czarniecka
Agnieszka Czarniecka
The Oncologic and Reconstructive Surgery Clinic, M. Sklodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland
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Renuka P Dias
Renuka P Dias
Department of Paediatric Endocrinology and Diabetes, Birmingham Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom
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Rossella Elisei
Rossella Elisei
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Louise Izatt
Louise Izatt
Department of Clinical Genetics, Guy's and St Thomas’ NHS Foundation Trust, London, United Kingdom
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Heiko Krude
Heiko Krude
Institute of Experimental Pediatric Endocrinology, Charité - Universitätsmedizin, Berlin, Germany
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Kerstin Lorenz
Kerstin Lorenz
Department of Visceral, Vascular and Endocrine Surgery, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany
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Markus Luster
Markus Luster
Department of Nuclear Medicine, University Hospital Marburg, Marburg, Germany
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Kate Newbold
Kate Newbold
Thyroid Therapy Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom
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Arnoldo Piccardo
Arnoldo Piccardo
Department of Nuclear Medicine, EO Ospedali Galliera, Genoa, Italy
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Manuel Sobrinho-Simões
Manuel Sobrinho-Simões
University Hospital of São João, Medical Faculty and Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal
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Toru Takano
Toru Takano
Thyroid Center, Rinku General Medical Center, Osaka, Japan
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A S Paul van Trotsenburg
A S Paul van Trotsenburg
Department of Pediatric Endocrinology, Emma Children's Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands
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Frederik A Verburg
Frederik A Verburg
Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
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Hanneke M van Santen
Hanneke M van Santen
Wilhelmina Children’s Hospital and Princess Máxima Center, Utrecht, The Netherlands
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population ( 6 , 7 , 8 ). The American Thyroid Association (ATA) has developed recommendations for pediatric nodules and thyroid carcinoma ( 8 ); however, in Europe, such recommendations are not yet available. Regulations for medical care differ between the
Rodrigo Moreno-Reyes
Rodrigo Moreno-Reyes
Department of Nuclear Medicine, Hospital Erasme, Université Libre de Bruxelles, Brussels, Belgium
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Endocrinology and Metabolism, University Hospital Rigshospitalet, and Faculty of Ηealth and Clinical Sciences, University of Copenhagen, Copenhagen, Denmark
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Agnieszka Piekiełko-Witkowska
Agnieszka Piekiełko-Witkowska
Centre of Postgraduate Medical Education, Centre of Translational Research, Department of Biochemistry and Molecular Biology, Warsaw, Poland: Basic Lead of the European Society of Endocrinology Focus Area on Thyroid
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Adriana Gaspar da Rocha
Adriana Gaspar da Rocha
Public Health Unit, ULS Baixo Mondego, Figueira da Foz, Portugal Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal Health Investigation and Innovation Institute (i3S), University of Porto, Porto, Portugal
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Corin Badiu
Corin Badiu
National Institute of Endocrinology "C. Davila" University of Medicine and Pharmacy, Bucharest, Romania
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Josef Köhrle
Josef Köhrle
Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Experimentelle Endokrinologie, Berlin, Germany: Co-Lead of the European Society of Endocrinology Focus Area on Environmental Endocrinology
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Leonidas Duntas
Leonidas Duntas
Evgenideion Hospital, Unit of Endocrinology, Metabolism and Diabetes, National Kapodistrian University of Athens, Athens, Greece
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Introduction Why is European Chemicals Agency’s (ECHA) statement not considered scientifically accurate by the thyroid community? The ECHA statement made in September 2022 ( 1 ) concluding that iodine is an endocrine disruptor (ED) and the
Giovanni Mauri
Giovanni Mauri
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy
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Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology, Odense University Hospital, University of Southern Denmark, Odense, Denmark
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Steven Bandula
Steven Bandula
Interventional Oncology Service, University College Hospital, London, United Kingdom
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Roberto Luigi Cazzato
Roberto Luigi Cazzato
Department of Interventional Radiology, University Hospital of Strasbourg, Strasbourg, France
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Agnieszka Czarniecka
Agnieszka Czarniecka
The Oncologic and Reconstructive Surgery Clinic, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
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Oliver Dudeck
Oliver Dudeck
Center for Microtherapy, Klinik Hirslanden, Zurich, Switzerland
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Laura Fugazzola
Laura Fugazzola
Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Romana Netea-Maier
Romana Netea-Maier
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Gilles Russ
Gilles Russ
Thyroid and Endocrine Tumors Unit, La Pitie-Salpetriere Hospital, Sorbonne University, Paris, France
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Göran Wallin
Göran Wallin
Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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Enrico Papini
Enrico Papini
Department of Endocrinology & Metabolism, Ospedale Regina Apostolorum, Albano, Italy
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Scope of the Document During the last decades, the incidence of differentiated thyroid cancer (DTC) is continuously rising in Europe and is estimated as high as 9 and 3 cases per 100,000 person-years in the female and male population
Benjamin Lallemant
Benjamin Lallemant
Departments of Head and Neck Surgery, University Hospital of Nîmes, Nîmes
University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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Guillaume Chambon
Guillaume Chambon
Departments of Head and Neck Surgery, University Hospital of Nîmes, Nîmes
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Camille Galy-Bernadoy
Camille Galy-Bernadoy
Departments of Head and Neck Surgery, University Hospital of Nîmes, Nîmes
University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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Héliette Chapuis
Héliette Chapuis
Departments of Pathology, University Hospital of Nîmes, Nîmes
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Anne-Marie Guedj
Anne-Marie Guedj
Endocrinology, University Hospital of Nîmes, Nîmes
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Huy Trang Pham
Huy Trang Pham
Departments of Head and Neck Surgery, University Hospital of Nîmes, Nîmes
University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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Jean-Gabriel Lallemant
Jean-Gabriel Lallemant
Departments of Head and Neck Surgery, University Hospital of Nîmes, Nîmes
University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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Damien Rupp
Damien Rupp
Departments of Head and Neck Surgery, University Hospital of Nîmes, Nîmes
University of Montpellier I, Sud de France, Montpellier, France
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University of Montpellier I, Sud de France, Montpellier, France
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avoided a visible scare on the neck and chest [ 2 , 3 , 4 ]. As this technique has become increasingly popular among patients, European surgeons have introduced it to their clinical practice resulting in several practical issues. Firstly, apart from the
Kris Poppe
Kris Poppe
Endocrine Unit, Department of Internal Medicine, University Hospital UZ Brussel (VUB), Brussels, Belgium
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Alicja Hubalewska-Dydejczyk
Alicja Hubalewska-Dydejczyk
Department of Endocrinology, Jagiellonian University Medical College, Kraków, Poland
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Peter Laurberg
Peter Laurberg
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
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Roberto Negro
Roberto Negro
Division of Endocrinology, V. Fazzi Hospital, Lecce
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Francesco Vermiglio
Francesco Vermiglio
Cattedra di Endocrinologia, Policlinico Universitario, Messina, Italy
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Bijay Vaidya
Bijay Vaidya
Department of Endocrinology, Royal Devon & Exeter Hospital, Exeter, UK
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to assess how European clinicians manage hyperthyroidism in pregnant women and to what extent their clinical practice is consistent with these guidelines. Participants and Methods In December 2010, an electronic questionnaire survey was e
Henry Völzke
Henry Völzke
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Iris Erlund
Iris Erlund
Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland
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Alicja Hubalewska-Dydejczyk
Alicja Hubalewska-Dydejczyk
Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
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Till Ittermann
Till Ittermann
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Robin P. Peeters
Robin P. Peeters
Department of Internal Medicine, Rotterdam Thyroid Centre, Erasmus Medical Centre, Rotterdam, The Netherlands
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Margaret Rayman
Margaret Rayman
University of Surrey, Surrey, United Kingdom
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Monika Buchberger
Monika Buchberger
Department of Public Health and Health Technology Assessment, UMIT, University for Health Science, Medical Informatics and Technology, Hall, Austria
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Uwe Siebert
Uwe Siebert
Department of Public Health and Health Technology Assessment, UMIT, University for Health Science, Medical Informatics and Technology, Hall, Austria
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Betina H. Thuesen
Betina H. Thuesen
Research Centre for Prevention and Health, Glostrup, Denmark
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Michael B. Zimmermann
Michael B. Zimmermann
Swiss Federal Institute of Technology, Zürich Department of Health Sciences and Technology, Zürich, Switzerland
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Stefan Grünert
Stefan Grünert
Biolution GmbH, Vienna, Austria
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John H. Lazarus
John H. Lazarus
Institute of Molecular Medicine, Cardiff University, Cardiff, United Kingdom
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[ 1 ]. Iodine deficiency during pregnancy and breast feeding is widespread in Europe and adversely affects the development of the child [ 1 ]. Adults living in iodine-deficient regions carry a high risk of goiter, thyroid nodules and hyperthyroidism
Diogo Mendes
Diogo Mendes
Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
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Carlos Alves
Carlos Alves
Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal
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Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal
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Nuno Silverio
Nuno Silverio
Merck S.A., Algés, Portugal
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Francisco Batel Marques
Francisco Batel Marques
Center for Health Technology Assessment and Drug Research, Association for Innovation and Biomedical Research on Light and Image, Coimbra, Portugal
Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal
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Laboratory of Social Pharmacy and Public Health, School of Pharmacy, University of Coimbra, Coimbra, Portugal
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European prevalence and incidence of (undiagnosed and diagnosed) thyroid dysfunction has been published, that work considered only studies that reported simultaneously on both hypo- and hyperthyroidism. This approach led to the exclusion of studies that
Roberto Negro
Roberto Negro
Division of Endocrinology, V. Fazzi Hospital, Lecce, Italy
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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Roberto Attanasio
Roberto Attanasio
Endocrine Unit, IRCCS Istituto Galeazzi, Milan, Italy
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Enrico Papini
Enrico Papini
Department of Endocrinology and Metabolism, Ospedale Regina Apostolorum, Rome, Italy
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Kristian H. Winther
Kristian H. Winther
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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[ 4 ] and is associated with excess morbidity and mortality [ 5 , 6 ]. Questionnaires by American Endocrine Societies (The Endocrine Society, American Thyroid Association and American Association of Clinical Endocrinologists) and the European Thyroid
Kristian Hillert Winther
Kristian Hillert Winther
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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Enrico Papini
Enrico Papini
Department of Endocrinology and Metabolism, Ospedale Regina Apostolorum, Rome, Italy
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Roberto Attanasio
Roberto Attanasio
Endocrine Unit, IRCCS Galeazzi Institute, Milan, Italy
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Roberto Negro
Roberto Negro
Division of Endocrinology, V. Fazzi Hospital, Lecce, Italy
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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course of the past 20 years, with more than 20 published trials, predominantly from Europe and China. One general conclusion from those trials, as summarized in several systematic reviews, is that Se supplementation decreases thyroid autoantibody
Cosimo Durante
Cosimo Durante
Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology, Odense University Hospital, Odense, Denmark
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Agnieszka Czarniecka
Agnieszka Czarniecka
M. Sklodowska-Curie National Research, Institute of Oncology Gliwice Branch, Gliwice, Poland
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Ralf Paschke
Ralf Paschke
Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Gilles Russ
Gilles Russ
Thyroid and Endocrine Tumors Department, Pitié-Salpêtrière Hospital, Sorbonne University GRC N°16, Paris, France
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Fernando Schmitt
Fernando Schmitt
Faculty of Medicine of University of Porto, CINTESIS@RISE and Institute of Molecular Pathology and Immunology, University of Porto (Ipatimup), Porto, Portugal
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Paula Soares
Paula Soares
Institute of Investigation and Innovation in Health (I3S), Faculty of Medicine of the University of Porto, Porto, Portugal
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Tamas Solymosi
Tamas Solymosi
Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary
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Enrico Papini
Enrico Papini
Department of Endocrine and Metabolic Diseases, Regina Apostolorum Hospital, Albano, Rome, Italy
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managed conservatively ( 4 ). Accepting that not all reasons for surgery are disclosed in the available literature, in European countries a proportion of such lesions are superfluously referred for surgery, leading to an unfavorable risk and cost
