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Elske T. Massolt Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

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Mahdi  Salih Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands

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Carolien M. Beukhof Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

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Boen L.R. Kam Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands

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J.W. Burger Division of Surgical Oncology, Department of Surgery, Erasmus MC, Rotterdam, The Netherlands

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W. Edward Visser Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

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Ewout J. Hoorn Department of Nephrology and Transplantation, Erasmus MC, Rotterdam, The Netherlands

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Robin P. Peeters Division of Endocrinology, Erasmus MC, Rotterdam, The Netherlands
Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands

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organs resulting in a variety of clinical symptoms [ 1 ]. The ability to conserve water during periods of water deprivation is an important function of the kidney. Fluid deprivation increases serum osmolality and thereby causes a release of the

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Wolfgang J. Schnedl Practice for General Internal Medicine, Bruck/Mur

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Siroos Mirzaei Department of Nuclear Medicine, Wilhelminenspital, Vienna

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Sandra J. Wallner-Liebmann Institute of Pathophysiology, Centre for Molecular Medicine, Medical University of Graz

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Erwin Tafeit Institute of Physiological Chemistry, Centre of Physiological Medicine, Medical University of Graz

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Harald Mangge Clinical Institute of Medical and Chemical Laboratory Diagnosis, Medical University of Graz

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Robert Krause Departments of Internal Medicine, Medical University of Graz, Graz, Austria

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Rainer W. Lipp Radiology, Medical University of Graz, Graz, Austria

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control her seizures with carbamazepine was started. This therapy was continued until the year 1999, although without clinical benefit. Therefore, the patient underwent another examination. During an electroencephalogram with sleep deprivation, again with

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Theodora Pappa Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital

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Maria Alevizaki Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital
Department of Endocrinology, Metabolism and Diabetes, Evgenideion Hospital, Athens University School of Medicine, Athens, Greece

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the activation of AMPK, which induces catabolism and downregulates cell proliferation by mimicking a state of caloric deprivation [ 7 , 29 ]. A recent review has provided an update on the potential role of metformin against cancer and a summary of

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Ángel García-Aldea Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain

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Marina Guillén-Yunta Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain

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Víctor Valcárcel-Hernández Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain

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Ana Montero-Pedrazuela Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain

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Ana Guadaño-Ferraz Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain

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Soledad Bárez-López Instituto de Investigaciones Biomédicas Sols-Morreale, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain

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critically dependent on TH signalling. Hearing loss in humans has been associated with iodine deficiency and congenital hypothyroidism ( 15 , 16 ). Audition takes place in the cochlea, which is the hearing organ located at the inner ear. This fluid

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Josef Köhrle Institut für Experimentelle Endokrinologie, Charité Campus Virchow-Klinikum (CVK), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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.1089/thy.2016.0532 28088877 1050-7256 65 Hüfner M , Grussendorf M , Lorenz U , Knöpfle M . 3,3′,5′-Triiodothyronine (Reverse T3) in amniotic fluid and cord serum . Eur J Pediatr . 1977 Jul ; 125 ( 3 ): 213 – 7 . 10.1007/BF00480599

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