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  • Follicular neoplasm x
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Kaoru Kobayashi Kuma Hospital, Kobe, Japan

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Hisashi Ota Kuma Hospital, Kobe, Japan

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Mitsuyoshi Hirokawa Kuma Hospital, Kobe, Japan

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Tomonori Yabuta Kuma Hospital, Kobe, Japan

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Mitsuhiro Fukushima Kuma Hospital, Kobe, Japan

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Hiroo Masuoka Kuma Hospital, Kobe, Japan

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Takuya Higashiyama Kuma Hospital, Kobe, Japan

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Minoru Kihara Kuma Hospital, Kobe, Japan

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Yasuhiro Ito Kuma Hospital, Kobe, Japan

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Akihiro Miya Kuma Hospital, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Kobe, Japan

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follicular carcinoma or follicular neoplasm within benign tumors histopathologically. The ultrasonographic significance of this appearance has not been clarified. What Does This Case Report Add? • A small number of follicular carcinoma cases or

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000452971
Volume/Issue:
Volume 6: Issue 2
Free access
Tumay Ozgur Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Hasan Gokce Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Ihsan Ustun Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Yaldiz Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Mustafa Akin Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Cumali Gokce Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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infiltrates [ 3 ]. RT is more common in females, with an operative incidence of 0.06% reported [ 4 ]. Follicular adenoma (FA) of the thyroid accounts for over 90% of benign neoplasms of the gland. FA may present with a range of patterns, from the classical

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000342628
Volume/Issue:
Volume 1: Issue 3
Free access
Dong Gyu Na Department of Radiology, Human Medical Imaging and Intervention Center, Seoul, South Korea

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Hye Sook Min Departments of Pathology, Seoul, South Korea

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Hunkyung Lee Department of Pathology, Ewha Clinical Laboratory, Seoul, South Korea

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Jae-Kyung Won Departments of Pathology, Seoul, South Korea

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Hyo Bin Seo Department of Radiology, Seoul National University Hospital Kangnam Center, Seoul, South Korea

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Ji-Hoon Kim Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea

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subcategory included nodules with architectural atypia such as the presence of a prominent population of microfollicles or Hurthle cells in sparsely cellular aspirates with scant colloid, but not enough to be diagnosed as a follicular neoplasm or suspicious

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000437051
Volume/Issue:
Volume 4: Issue 3
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Mario Monaco Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Gennaro Chiappetta Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Concetta Aiello Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Antonella Federico Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Romina Sepe Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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Daniela Russo Istituto Nazionale per lo Studio e la Cura dei Tumori ‘Fondazione Giovanni Pascale', IRCCS, Italy

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Alfredo Fusco Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy
Instituto Nacional de Câncer - INCA, Rio de Janeiro, Brazil

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Pierlorenzo Pallante Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli ‘Federico II', Naples, Italy

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hematogenously. The overall mortality rates range from 9 to 28% [ 11 , 12 , 13 , 14 , 15 ]. According to the World Health Organization (WHO), these neoplasms are considered a variant of follicular carcinoma of the thyroid and are referred to as follicular

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000367989
Volume/Issue:
Volume 3: Issue 4
Free access
Kassia B. Reuters Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Maria C.O.C. Mamone Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Elsa S. Ikejiri Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Cleber P. Camacho Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Claudia C.D. Nakabashi Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Carolina C.P.S. Janovsky Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Ji H. Yang Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Danielle M. Andreoni Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Rosalia Padovani Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Santa Casa de São Paulo, São Paulo, Brazil

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Rui M.B. Maciel Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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Felipe A.B. Vanderlei Head and Neck Division, Department of Otorhinolaryngology and Head and Neck Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Rosa P.M. Biscolla Thyroid Diseases Center and Laboratory of Molecular and Translational Endocrinology, Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil

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), follicular neoplasm or suspicious for follicular neoplasm (FN/SFN, Bethesda IV), suspicious for malignancy (SM, Bethesda V), and malignant (Bethesda VI) [ 11 - 13 ]. Since its publication, several centers in different countries have applied the Bethesda

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000488104
Volume/Issue:
Volume 7: Issue 3
Free access
Ralf Paschke
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Silvia Cantara
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Anna Crescenzi
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Barbara Jarzab
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Thomas J. Musholt
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Manuel Sobrinho Simoes
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) atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS); (IV) follicular neoplasm/suspicious for follicular neoplasm (FN/SFN), a category that also encompasses the diagnosis of Hürthle cell neoplasm/suspicious for

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000468519
Volume/Issue:
Volume 6: Issue 3
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Dorothée Bouron-Dal Soglio Department of Pathology, CHU Sainte-Justine, Montreal, Québec, Canada

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Leanne de Kock The Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada

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Richard Gauci Nuclear Medicine, Sir Charles Gairdner Hospital, Nedlands, Washington, Australia

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Nelly Sabbaghian The Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Québec, Canada

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Elizabeth Thomas Nuclear Medicine, Sir Charles Gairdner Hospital, Nedlands, Washington, Australia
Department of Endocrinology and Diabetes, Princess Margaret Hospital for Children, Subiaco, Washington, Australia

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Helen C. Atkinson Faculty of Health and Medical Sciences, School of Medicine, The University of Western Australia, Crawley, Washington, Australia

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Nicholas Pachter Faculty of Health and Medical Sciences, School of Medicine, The University of Western Australia, Crawley, Washington, Australia
King Edward Memorial Hospital, Perth, Washington, Australia

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Simon Ryan Department of General Surgery, Sir Charles Gairdner Hospital, Nedlands, Washington, Australia

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John P. Walsh Faculty of Health and Medical Sciences, School of Medicine, The University of Western Australia, Crawley, Washington, Australia
Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Washington, Australia

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M. Priyanthi Kumarasinghe PathWest, QEII Medical Centre, Perth, Washington, Australia

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Karen Carpenter Department of Diagnostic Genomics, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, Washington, Australia

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Ayça Aydoğan Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey

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Colin J.R. Stewart King Edward Memorial Hospital, Perth, Washington, Australia

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William D. Foulkes The Lady Davis Institute, Segal Cancer Centre, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada
Department of Medical Genetics, Research Institute of the McGill University Health Centre, Montreal, Québec, Canada

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Catherine S. Choong Department of Endocrinology and Diabetes, Princess Margaret Hospital for Children, Subiaco, Washington, Australia
Faculty of Health and Medical Sciences, School of Medicine, The University of Western Australia, Crawley, Washington, Australia

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). Ultrasound-guided fine needle aspiration (FNA) cytology revealed a follicular neoplasm and the patient underwent a right hemithyroidectomy in October 2007. Histopathological examination revealed 2 thyroid nodules (Fig 2 a, b). The first was a 35 mm

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000481620
Volume/Issue:
Volume 7: Issue 1
Free access
Catherine Brophy Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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Rania Mehanna Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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Julie McCarthy Departments of Cytopathology, Cork University Hospital, Cork, Ireland

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Antoinette Tuthill Departments of Endocrinology, Cork University Hospital, Cork, Ireland

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Matthew S. Murphy Departments of Endocrinology, South Infirmary Victoria University Hospital, Cork, Ireland

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Patrick Sheahan Departments of Otolaryngology - Head and Neck Surgery, Cork, Ireland

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(follicular neoplasm) [ 4 ]. The Thy-3f category is used for cases which are cytologically suspicious for a follicular or Hürthle cell neoplasm (analogous to the Bethesda follicular neoplasm category), whereas the Thy-3a category is used for cases

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000441221
Volume/Issue:
Volume 4: Issue 4
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Rachelle P Mendoza Department of Pathology, University of Rochester Medical Center, Rochester, New York, USA

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Richard Cody Simon Department of Pathology, University of Chicago, Chicago, Illinois, USA

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Nicole A Cipriani Department of Pathology, University of Chicago, Chicago, Illinois, USA

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Tatjana Antic Department of Pathology, University of Chicago, Chicago, Illinois, USA

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documented. There was no noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) identified in this cohort. The study was approved by the University of Chicago Institutional Review Board (IRB22-1207). The cytologic diagnosis of

Article Type:
Research Article
Collections:
Goiter and thyroid nodules
DOI:
https://doi.org/10.1530/ETJ-23-0153
Volume/Issue:
Volume 13: Issue 1
Open access
Nooshin Zargari Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran

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Maral Mokhtari Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran

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Introduction Thyroid lesions with a follicular pattern, which is defined as the cells arranged around a central lumen containing colloid material, consist of a large group of thyroid neoplasms, including follicular adenoma (FA), follicular

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000494430
Volume/Issue:
Volume 8: Issue 1
Free access