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Mohamed E. Ahmed Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan

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Mohamed A. Mahgoub Khartoum Teaching Hospital, Khartoum, Sudan

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Mohamed G. Alnedar Khartoum Teaching Hospital, Khartoum, Sudan

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Seif I. Mahadi Khartoum Teaching Hospital, Khartoum, Sudan
Departments of Medicine, Khartoum, Sudan

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Maha Alzubeir Surgery, Faculty of Medicine, Khartoum, Sudan

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Lamyaa A.M. El Hassan University of Ahfad, Khartoum, Sudan

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ElWaleed M. Elamin Alzaeim Alazhari University, Khartoum, Sudan

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Ahmed Mohammed El Hassan University of Khartoum, Khartoum, Sudan

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What Is Known about This Topic • There has been one previous case report on the coexistence of thymoma and intrathoracic goiter with an uncomplicated postoperative course. Myasthenic crisis occurs postoperatively in one third of thymoma

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Filip Alsted Brinch Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark

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Helle Døssing Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark

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Nina Nguyen Department of Radiology, Odense University Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Christian Godballe Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark

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Jesper Roed Sorensen Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark
OPEN, Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark

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goiter can lead to a wide range of symptoms including swallowing discomfort and respiratory disturbances, which can have a negative impact on quality of life (QoL) [ 1 , 5 , 6 ]. A clear correlation between goiter volume, tracheal compression, and

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Jesper Roed Sorensen Department of ORL Head and Neck Surgery, Odense University Hospital, Odense, Denmark
OPEN, Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark

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Jeppe Faurholdt Lauridsen Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark

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Helle Døssing Department of ORL Head and Neck Surgery, Odense University Hospital, Odense, Denmark

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Nina Nguyen Department of Radiology, Odense University Hospital, Odense, Denmark

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Christian Godballe Department of ORL Head and Neck Surgery, Odense University Hospital, Odense, Denmark

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Introduction Benign nodular goiter is common in the adult population [ 1 ]. While iodization programs and alterations in smoking behavior have reduced the impact of the major environmental triggers, awareness of therapeutic modalities remains

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Steen J. Bonnema Departments of Endocrinology, Odense University Hospital, Odense

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Elisabeth S. Stovgaard Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

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Søren Fast Departments of Endocrinology, Odense University Hospital, Odense

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Kasper Broedbaek Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

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Jon T. Andersen Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

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Allan Weimann Laboratory of Clinical Pharmacology Q7642, Rigshospitalet

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Peter Grupe Departments of Nuclear Medicine, Odense University Hospital, Odense

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Laszlo Hegedüs Departments of Endocrinology, Odense University Hospital, Odense

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Henrik E. Poulsen Laboratory of Clinical Pharmacology Q7642, Rigshospitalet
Department of Clinical Pharmacology, Bispebjerg Hospital
Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark

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Introduction For many years radioactive iodine ( 131 I) has been used for treatment of nontoxic goiter, hyperthyroidism and thyroid cancer. During the last decade recombinant human TSH (rhTSH) - a very potent stimulator of the thyroid 131 I

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Omar Abdul Hameed Ali Department of Surgery, University Charity and Teaching Hospital and Khartoum Breast Care Center

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Abdul Fatah Abdul Gadir Department of Pathology, University of Medical Sciences and Technology, Khartoum, Sudan

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Introduction Iodine deficiency disorders constitute a severe public health problem in Sudan. It affects children and women throughout life. More than 2 out of 10 school age children have goiter [ 1 ]. Dietary iodine intake was reported to be

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Tina Toft Kristensen Department of Otorhinolaryngology, Head and Neck Surgery, Køge Hospital, Region Zealand, Køge

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Jacob Larsen Departments of Clinical Pathology, Næstved Hospital, Region Zealand, Næstved, Denmark

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Palle Lyngsie Pedersen Departments of Clinical Biochemistry, Næstved Hospital, Region Zealand, Næstved, Denmark

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Anne-Dorthe Feldthusen Departments of Gynecology and Obstetrics, Næstved Hospital, Region Zealand, Næstved, Denmark

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Christina Ellervik Departments of Clinical Biochemistry, Næstved Hospital, Region Zealand, Næstved, Denmark

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Søren Jelstrup Department of Otorhinolaryngology, Head and Neck Surgery, Køge Hospital, Region Zealand, Køge

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Jan Kvetny Internal Medicine, Næstved Hospital, Region Zealand, Næstved, Denmark

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, focusing on tissue response to hemithyroidectomy-induced thyroid functional changes by examining the mitochondrial function of peripheral blood mononuclear cells (PBMCs) before and during the first year after hemithyroidectomy for benign euthyroid goiter

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Mafalda Marcelino Department of Endocrinology, Armed Forces University Hospital, Lisbon, Portugal
Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal

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Pedro Marques Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal

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Luis Lopes Department of Endocrinology, Armed Forces University Hospital, Lisbon, Portugal

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Valeriano Leite Department of Endocrinology, Portuguese Institute of Oncology, Lisbon, Portugal

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João Jácome de Castro Department of Endocrinology, Armed Forces University Hospital, Lisbon, Portugal

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]. Larger and prospective studies are required to evaluate this issue. Moreover, there are some data reporting unusual toxic thyroid carcinomas [ 9 ], and recent studies suggest that the frequency of malignancy in toxic multinodular goiter (TMNG) is

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Katarzyna Pelewicz Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Rafał Wolny Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland

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Tomasz Bednarczuk Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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Piotr Miśkiewicz Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland

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functioning nodular goiters are at higher risk of developing this dysfunction [ 3 ]. The risk of goiter development is higher in the area of iodine deficiency [ 4 ]. Deficient iodine intake may impact the secretion of thyroid-stimulating hormone (TSH), causing

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Yun Jeong Lee Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea

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Young Hun Choi Department of Radiology, Seoul National University Hospital, Seoul, Korea

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Youn-Hee Lim Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea
Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea

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Bung-Nyun Kim Division of Children and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea

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Johanna Inhyang Kim Department of Psychiatry, Hanyang University Medical Center, Seoul, Republic of Korea

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Yun-Chul Hong Institute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea
Environmental Health Center, Seoul National University College of Medicine, Seoul, Republic of Korea
Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Young Joo Park Department of Internal medicine, Seoul National University Hospital, Seoul, Republic of Korea
Department of Internal medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Choong Ho Shin Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea

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Sun Wook Cho Department of Internal medicine, Seoul National University Hospital, Seoul, Republic of Korea
Department of Internal medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

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Young Ah Lee Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea

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Introduction Adequate iodine intake is essential in growing children because both iodine deficiency and excess can adversely affect thyroid function ( 1 , 2 ). Thyroid volume (Tvol) and goiter rate have been regarded as indicators of the long

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Selwan Khamisi Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden

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Peter Lindgren Women's and Children's Health, University Hospital, Uppsala University, Uppsala, Sweden

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F. Anders Karlsson Department of Endocrinology and Diabetes, Uppsala University, Uppsala, Sweden

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Introduction Development of a fetal goiter reflects inadequate thyroid hormone production. A large goiter can cause premature labor due to polyhydramnios (impaired fetal swallowing of amniotic fluid), and cause complications

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