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Claudio Marcocci Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy

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Marenza Leo Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy

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Maria Antonietta Altea Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy

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, elevated intracellular ATP consumption, and increased ROS production [ 5 , 6 ]. Moreover, there is evidence supporting a role of oxidative processes in the genesis of Graves’ disease (GD) [ 7 ], hyperthyroidism-induced damage such as thyrotoxic myopathy and

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000337976
Volume/Issue:
Volume 1: Issue 2
Free access
Mats Holmberg ANOVA, Karolinska University Hospital, Norra Stationsgatan 69, Stockholm, Sweden
Institute of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden
Wallenberg’s Centre of Molecular and Translational Medicine, Region Västra Götaland, Sweden

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Helge Malmgren Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Peter F Berglund Institute of Neuroscience and Physiology, Department of Clinical Neuroscience, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Birgitta Johansson Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden

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Helena Filipsson Nyström Wallenberg’s Centre of Molecular and Translational Medicine, Region Västra Götaland, Sweden
Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Göteborg, Sweden
Gothenburg Centre for Person Centred-Care (GPCC), Göteborg, Sweden

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mental symptoms may be a consequence of the elevated thyroid hormones, the autoimmune reaction, the circumstance that persons with psychiatric conditions may be more prone to develop Graves’ disease (GD), the development of complications like thyroid

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-23-0247
Volume/Issue:
Volume 13: Issue 1
Open access
Hiroki Kobayashi Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Akira Haketa Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Masanori Abe Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Kazunobu Tahira Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Yoshinari Hatanaka Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Sho Tanaka Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Takahiro Ueno Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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Masayoshi Soma Division of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

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thyrotoxicosis [ 4 ]. However, some reports have demonstrated other causes of VF [ 5 , 6 ]. We report here a case of Graves' disease with VF as the result of thyrotoxicosis and review the literature on VF associated with thyrotoxicosis. This case suggests that

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000437225
Volume/Issue:
Volume 4: Issue 3
Free access
John H. Lazarus Centre for Endocrine and Diabetes Sciences, Cardiff University, Cardiff, UK

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gestation. In contrast, TSH receptor antibodies have a prevalence of around 0.01%, but neonatal hyperthyroidism occurs in 30% of TSH receptor antibody-positive women [ 2 ]. Course of Graves’ Disease during Pregnancy Deterioration in the clinical

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000336102
Volume/Issue:
Volume 1: Issue 1
Free access
Luigi Bartalena Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy

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Introduction Management of Graves' orbitopathy (GO), the most important extrathyroidal expression of Graves' disease, remains a major challenge and dilemma [ 1 ]. Available therapies are largely imperfect, and a large proportion of patients

Article Type:
Review Article
DOI:
https://doi.org/10.1159/000356042
Volume/Issue:
Volume 2: Issue 4
Free access
Cosimo Rodia Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Francesca Menconi Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Laura Mazoni Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Liborio Torregrossa Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Fulvio Basolo Department of Surgical, Medical and Molecular Pathology, Pathology Unit, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Claudio Marcocci Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Michele Marinò Department of Clinical and Experimental Medicine, Endocrinology Units, University of Pisa and University Hospital of Pisa, Pisa, Italy

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What Is Known about this Topic? Thyroid dermopathy is a rare extrathyroidal manifestation of Graves’ disease (GD). It is usually bilateral, but monolateral variants can be observed. As for Graves’ orbitopathy, the most common

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000500297
Volume/Issue:
Volume 8: Issue 5
Free access
Kira Bang Bové Department of Endocrinology, Odense, Denmark

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Torquil Watt Department of Endocrinology, Odense, Denmark
Institute of Public Health, University of Copenhagen, Odense, Denmark

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Asmus Vogel Memory Disorders Research Group, Department of Neurology, Copenhagen University Hospital, Rigshospitalet, Odense, Denmark

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Jakob Bue Bjoerner Institute of Public Health, University of Copenhagen, Odense, Denmark
National Research Centre for the Working Environment, Copenhagen, Odense, Denmark

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Mogens Groenvold Institute of Public Health, University of Copenhagen, Odense, Denmark
Department of Palliative Medicine, Bispebjerg Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Åse Krogh Rasmussen Department of Endocrinology, Odense, Denmark

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Ulla Feldt-Rasmussen Department of Endocrinology, Odense, Denmark

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depression [ 2 , 3 , 4 , 5 , 6 ] but increased prevalence of anxiety and depression is also found in hyperthyroidism [ 7 ], particularly in the early phase of Graves' disease [ 8 , 9 , 10 , 11 ], compared with the general population or compared with patients

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000365211
Volume/Issue:
Volume 3: Issue 3
Free access
Shi Hui Junice Wong Department of General Surgery, Tan Tock Seng Hospital, Singapore, Singapore

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Established Facts Radioiodine (RAI) therapy for Graves’ disease is generally well tolerated. RAI therapy can rarely cause radiation-induced thyroiditis, but this is self-limiting and localized to the thyroid gland. Novel

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000503457
Volume/Issue:
Volume 8: Issue 6
Free access
N. Papanikolaou Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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P. Perros Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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thyrotoxicosis and resolves rapidly after euthyroidism is restored. • Awareness of this very rare manifestation of thyrotoxicosis may obviate the need to seek alternative diagnoses. Introduction Graves’ disease is the commonest cause of thyrotoxicosis

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000343826
Volume/Issue:
Volume 1: Issue 4
Free access
Alessandro Brancatella Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Nicola Viola Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Sandra Brogioni Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Lucia Montanelli Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Chiara Sardella Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Claudio Marcocci Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Isabella Lupi Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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Francesco Latrofa Department of Clinical and Experimental Medicine, Unit of Endocrinology, University of Pisa, Pisa, Italy

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contrary, Graves’ disease has been described in only eight patients during ICPis treatment, five during anti-CTLA-4 and three during anti-PD-1 treatment. We report the fourth case of Grave’s disease induced by anti-PD-1, the second with an overt

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000501824
Volume/Issue:
Volume 8: Issue 4
Free access