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Kris Poppe Endocrine Unit, Department of Internal Medicine, University Hospital UZ Brussel (VUB), Brussels, Belgium

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Alicja Hubalewska-Dydejczyk Department of Endocrinology, Jagiellonian University Medical College, Kraków, Poland

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Peter Laurberg Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark

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Roberto Negro Division of Endocrinology, V. Fazzi Hospital, Lecce

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Francesco Vermiglio Cattedra di Endocrinologia, Policlinico Universitario, Messina, Italy

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Bijay Vaidya Department of Endocrinology, Royal Devon & Exeter Hospital, Exeter, UK

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and this is not associated with an adverse pregnancy outcome [ 2 , 3 ]. GD and GTT must be distinguished from each other because their clinical courses, associated risks for the mother and the fetus, and the management are different. In general the

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Ilaria Muller Thyroid Research Group, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

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Carla Moran Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom

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Beatriz Lecumberri Department of Endocrinology and Nutrition, La Paz University Hospital, IdiPAZ, Autonomous University of Madrid, Madrid, Spain

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Brigitte Decallonne Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium

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Neil Robertson Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom

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Joanne Jones Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom

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Colin M. Dayan Thyroid Research Group, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

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) before the TD onset following HAART in a small patient cohort [ 17 ]; therefore, the detection of preclinical disease would not alter the monitoring or management of TD. Recommendation 7. We do not recommend routine measurement of thyroid

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Min Ji Jeon Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Won Gu Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Ki-Wook Chung Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Jung Hwan Baek Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Won Bae Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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Young Kee Shong Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

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that most PTMCs have a very indolent nature and excellent outcomes [ 2 , 5 , 6 ]. Recently, active surveillance (AS) instead of immediate surgery was suggested as a management option for PTMCs [ 6 - 8 ]. By definition, AS means applying life

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George J. Kahaly Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, Mainz, Germany

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Luigi Bartalena Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Lazlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Laurence Leenhardt Thyroid and Endocrine Tumors Unit, Pitié Salpêtrière Hospital, Sorbonne University, Paris, France

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Kris Poppe Endocrine Unit, CHU Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Simon H. Pearce Department of Endocrinology, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

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nodularity coexists with hyperthyroidism, and prior to RAI therapy. 2, ∅∅∅○ Management Medical Treatment Graves’ hyperthyroidism is treated by reducing TH synthesis, using ATD, or by reducing the amount of thyroid tissue with RAI treatment or

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John Lazarus Thyroid Research Group, Institute of Molecular Medicine, Cardiff University, University Hospital of Wales, Cardiff

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Rosalind S. Brown Clinical Trials Research Division of Endocrinology, Children's Hospital Boston, Harvard Medical School, Boston, Mass., USA

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Chantal Daumerie Endocrinologie, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Alicja Hubalewska-Dydejczyk Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland

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Roberto Negro Division of Endocrinology, V. Fazzi Hospital, Lecce, Italy

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Bijay Vaidya Department of Endocrinology, Royal Devon and Exeter Hospital and University of Exeter Medical School, Exeter, UK

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. During the last 2 decades advances in our understanding of thyroid physiology in pregnancy have led to the appreciation of the adverse effects of SCH on both the mother and child. Furthermore, considerable variation in the management of SCH in pregnancy

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Shigenobu Nagataki Nagasaki University, Ito Hospital, and Radiation Effects Association, Tokyo, Japan

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ultrasound examination program, i.e. the Fukushima Health Management Survey [ 1 , 2 ]. The first cycle of examinations was conducted to the 2013 fiscal year on all children of the Fukushima Prefecture (residents aged 0-18 years at the time of the accident

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Bernadette Biondi Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy

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Luigi Bartalena Department of Clinical and Experimental Medicine, University of Insubria, Endocrine Unit, Ospedale di Circolo, Varese, Italy

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David S. Cooper Division of Endocrinology, Diabetes, and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Md., USA

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Peter Laurberg Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark

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George J. Kahaly Department of Medicine I, Johannes Gutenberg University Medical Center, Mainz, Germany

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-spine fractures) [ 71 , 75 , 108 , 109 ] (1/++0). Fig. 1 Algorithm for the management of SHyper. a TSHR-Abs = TSH-receptor antibodies. b Grade 1 SHyper (TSH levels: 0.1-0.39 mIU/l). c Grade 2 SHyper (TSH levels <0.1 mIU/l). d RAI in patients with

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Patrick W. Owens Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Terri P. McVeigh Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland
Cancer Genetics Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom

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Eoin J. Fahey Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Marcia Bell Department of Endocrinology, Galway University Hospital, Galway, Ireland

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Denis S. Quill Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Michael J. Kerin Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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Aoife J. Lowery Discipline of Surgery, Lambe Institute for Translational Research, NUI Galway, Galway, Ireland

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radioiodine remnant ablation (RRA); it follows that overdiagnosis of DTC results in potentially avoidable morbidity arising from surgical or RRA therapies. The key recommendations of the British Thyroid Association (BTA) 2014 guidelines for the management of

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Cosimo Durante Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy

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Laszlo Hegedüs Department of Endocrinology, Odense University Hospital, Odense, Denmark

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Agnieszka Czarniecka M. Sklodowska-Curie National Research, Institute of Oncology Gliwice Branch, Gliwice, Poland

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Ralf Paschke Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

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Gilles Russ Thyroid and Endocrine Tumors Department, Pitié-Salpêtrière Hospital, Sorbonne University GRC N°16, Paris, France

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Fernando Schmitt Faculty of Medicine of University of Porto, CINTESIS@RISE and Institute of Molecular Pathology and Immunology, University of Porto (Ipatimup), Porto, Portugal

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Paula Soares Institute of Investigation and Innovation in Health (I3S), Faculty of Medicine of the University of Porto, Porto, Portugal

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Tamas Solymosi Endocrinology and Metabolism Clinic, Bugat Hospital, Gyöngyös, Hungary

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Enrico Papini Department of Endocrine and Metabolic Diseases, Regina Apostolorum Hospital, Albano, Rome, Italy

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without this leading to a significant lowering of thyroid cancer mortality ( 11 , 12 , 13 ). There is a pronounced need for more cost-effective, risk-adapted approaches to the management of this highly prevalent condition, taking the wishes of the

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Jingyue Chen Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Chenyan Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Weiping Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Zhongyan Shan Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Jun Jin Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yining Wei Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Jing Sun Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yushu Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Huifang Zhou Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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treatment. In 2008, the European Group on Graves’ Orbitopathy (EUGOGO) released a consensus statement on the treatment of Graves’ Orbitopathy (GO) ( 8 ). In 2016, the European Thyroid Association (ETA) collaborated with EUGOGO to publish the management

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