Jiahui Wu
Jiahui Wu
Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Xunyang Hu
Xunyang Hu
Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Paula Seal
Paula Seal
EFW Radiology, Calgary, Alberta, Canada
Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Parthiv Amin
Parthiv Amin
Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Brendan Diederichs
Brendan Diederichs
Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Mayfair Radiology, Calgary, Alberta, Canada
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Mayfair Radiology, Calgary, Alberta, Canada
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Ralf Paschke
Ralf Paschke
Section of Endocrinology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Departments of Medicine, Oncology, Pathology and Laboratory Medicine, Biochemistry and Molecular Biology, and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Departments of Medicine, Oncology, Pathology and Laboratory Medicine, Biochemistry and Molecular Biology, and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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Introduction Current postoperative follow-up (FU) and dynamic response to treatment (RTT) assessment of thyroid cancer primarily depends on postoperative neck ultrasound (POU) and thyroglobulin (Tg) determination ( 1 ). This FU strategy is
Vittoria Guarda
Vittoria Guarda
Department of Otolaryngology, Head and Neck Surgery, Technical University of Munich, Munich, Germany
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Anja Pickhard
Anja Pickhard
Department of Otolaryngology, Head and Neck Surgery, Technical University of Munich, Munich, Germany
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Melanie Boxberg
Melanie Boxberg
Institute of Pathology, Technical University of Munich, Munich, Germany
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Katja Specht
Katja Specht
Institute of Pathology, Technical University of Munich, Munich, Germany
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Anna Maria Stefanie Buchberger
Anna Maria Stefanie Buchberger
Department of Otolaryngology, Head and Neck Surgery, Technical University of Munich, Munich, Germany
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admission revealed a palpable painless tissue mass in the right cervical area. Protrusion of the posterior pharyngeal wall was observed during the endoscopic examination but no fixation of the vocal cords or subglottic stenosis. A neck ultrasound was
L. Leenhardt
L. Leenhardt
Department of Nuclear Medicine, Pitié Salpêtrière Hospital, Cancer Institute, Pierre et Marie Curie University, Paris, France
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M.F. Erdogan
M.F. Erdogan
Department of Endocrinology and Metabolism, University of Ankara School of Medicine, İbni Sina Hastanesi, Ankara, Turkey
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L. Hegedus
L. Hegedus
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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S.J. Mandel
S.J. Mandel
Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa., USA
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R. Paschke
R. Paschke
Department of Endocrinology, University of Leipzig, Leipzig, Germany
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T. Rago
T. Rago
Endocrine Unit 1, Department of Internal Medicine, Ospedale Cisanello, University of Pisa, Pisa, Italy
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G. Russ
G. Russ
Department of Nuclear Medicine, Pitié Salpêtrière Hospital, Cancer Institute, Pierre et Marie Curie University, Paris, France
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published guidelines, in the first 1-2 years after initial surgery and radioiodine treatment, risk restratification relies primarily on thyroglobulin (Tg) measurement and neck ultrasound (US). The usefulness of neck US for the assessment of therapeutic
Hélène Théodon
Hélène Théodon
Department of Thyroid and Endocrine Tumors, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Erell Guillerm
Erell Guillerm
Department of Oncogenetic, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Johanna Wassermann
Johanna Wassermann
Department of Oncology, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Gabrielle Deniziaut
Gabrielle Deniziaut
Department of Pathology, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Loïc Jaffrelot
Loïc Jaffrelot
Department of Oncology, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Jérome Denis
Jérome Denis
Department of Endocrine and Oncology Biochemistry, Sorbonne Université, Pitié-Salpêtrière Hospital, Paris, France
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Nathalie Chereau
Nathalie Chereau
Department of Endocrine Surgery, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Claude Bigorgne
Claude Bigorgne
Department of Pathology, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Wiame Potonnier
Wiame Potonnier
Department of Pathology, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Florence Coulet
Florence Coulet
Department of Oncogenetic, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Laurence Leenhardt
Laurence Leenhardt
Department of Thyroid and Endocrine Tumors, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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Camille Buffet
Camille Buffet
Department of Thyroid and Endocrine Tumors, Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Pitié-Salpêtrière Hospital, Paris, France
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unavailable, molecular testing on ultrasound (US)-guided fine needle aspirate (FNA) from a metastatic neck lymph node seems a suitable option as it is a minimally invasive procedure and neck lymph nodes are easily accessible. This genotyping strategy has been
Min Ren
Min Ren
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Qianlan Yao
Qianlan Yao
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Longlong Bao
Longlong Bao
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Zhiting Wang
Zhiting Wang
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Ran Wei
Ran Wei
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Qianming Bai
Qianming Bai
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Bo Ping
Bo Ping
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Cai Chang
Cai Chang
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Ultrasound, Fudan University Shanghai Cancer Center, Shanghai, China
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Department of Ultrasound, Fudan University Shanghai Cancer Center, Shanghai, China
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Yu Wang
Yu Wang
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
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Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
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Xiaoyan Zhou
Xiaoyan Zhou
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Xiaoli Zhu
Xiaoli Zhu
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
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, remain limited ( 3 , 4 , 5 ). Fine-needle aspiration (FNA) followed by cytological examination is the standard diagnostic procedure for patients with suspicious thyroid ultrasound features. The diagnoses of most FNA samples are classified into
Giovanni Mauri
Giovanni Mauri
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy
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Division of Interventional Radiology, European Institute of Oncology, IRCCS, Milan, Italy
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Laszlo Hegedüs
Laszlo Hegedüs
Department of Endocrinology, Odense University Hospital, University of Southern Denmark, Odense, Denmark
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Steven Bandula
Steven Bandula
Interventional Oncology Service, University College Hospital, London, United Kingdom
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Roberto Luigi Cazzato
Roberto Luigi Cazzato
Department of Interventional Radiology, University Hospital of Strasbourg, Strasbourg, France
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Agnieszka Czarniecka
Agnieszka Czarniecka
The Oncologic and Reconstructive Surgery Clinic, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland
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Oliver Dudeck
Oliver Dudeck
Center for Microtherapy, Klinik Hirslanden, Zurich, Switzerland
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Laura Fugazzola
Laura Fugazzola
Department of Endocrinology and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy
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Romana Netea-Maier
Romana Netea-Maier
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Gilles Russ
Gilles Russ
Thyroid and Endocrine Tumors Unit, La Pitie-Salpetriere Hospital, Sorbonne University, Paris, France
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Göran Wallin
Göran Wallin
Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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Enrico Papini
Enrico Papini
Department of Endocrinology & Metabolism, Ospedale Regina Apostolorum, Albano, Italy
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, Bianchini A , Coccaro C , . Ultrasound-guided laser ablation for local control of neck recurrences of medullary thyroid cancer. A feasibility study . Int J Hyperthermia . 2018 Dec ; 35 ( 1 ): 480 – 92 . http://dx.doi.org/10
Sara De Vincentis
Sara De Vincentis
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Simona Loiacono
Simona Loiacono
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
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Eleonora Zanni
Eleonora Zanni
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
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Roberta Sueri
Roberta Sueri
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
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Maria Laura Monzani
Maria Laura Monzani
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Daniele Santi
Daniele Santi
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Ilaria Muller
Ilaria Muller
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Department of Endocrinology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Department of Endocrinology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
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Francesco Di Marco
Francesco Di Marco
School of Specialisation in Endocrinology, University of Milan, Milan, Italy
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Erica Crivicich
Erica Crivicich
School of Specialisation in Endocrinology, University of Milan, Milan, Italy
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Mirco Armenti
Mirco Armenti
School of Specialisation in Endocrinology, University of Milan, Milan, Italy
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Uberto Pagotto
Uberto Pagotto
Department of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Bologna, Italy
Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy
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Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy
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Lorenzo Tucci
Lorenzo Tucci
Department of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Bologna, Italy
Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy
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Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy
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Carolina Cecchetti
Carolina Cecchetti
Department of Medical and Surgical Sciences, Alma Mater Studiorum - Bologna University, Bologna, Italy
Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy
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Department of Endocrinology and Diabetes Care and Prevention Unit, IRCCS Sant’Orsola-Malpighi Polyclinic, Bologna, Italy
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Tommaso Trenti
Tommaso Trenti
Department of Laboratory Medicine and Anatomy Pathology, Azienda USL Modena, Modena, Italy
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Valentina Pecoraro
Valentina Pecoraro
Department of Laboratory Medicine and Anatomy Pathology, Azienda USL Modena, Modena, Italy
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Giulia Canu
Giulia Canu
Department of Laboratory Medicine and Anatomy Pathology, Azienda USL Modena, Modena, Italy
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Manuela Simoni
Manuela Simoni
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Giulia Brigante
Giulia Brigante
Unit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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Unit of Endocrinology, Department of Medical Specialties, Azienda Ospedaliero-Universitaria of Modena, Modena, Italy
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been observed. SAT is a thyroid inflammatory disease characterized by follicle damage that usually presents with anterior neck pain that may radiate to the ears and jaw ( 2 ). Other systemic and laboratory findings of SAT include low-grade fever
Luca Damiani
Luca Damiani
Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
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Sabrina Lupo
Sabrina Lupo
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Roberta Rossi
Roberta Rossi
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Stefania Bruni
Stefania Bruni
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Mirco Bartolomei
Mirco Bartolomei
Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy
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Stefano Panareo
Stefano Panareo
Nuclear Medicine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy
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Paola Franceschetti
Paola Franceschetti
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Paolo Carcoforo
Paolo Carcoforo
Department of Morphology, Section of Surgery, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy
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Giovanni Lanza
Giovanni Lanza
Department of Medical Sciences, Pathology Unit, University of Ferrara, Ferrara, Italy
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Stefano Pelucchi
Stefano Pelucchi
Department of Biomedical and Surgical Specialization Sciences, University of Ferrara, Ferrara, Italy
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Ettore Degli Uberti
Ettore Degli Uberti
Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Maria Chiara Zatelli
Maria Chiara Zatelli
Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy
Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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Endocrine Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona/Ferrara, Italy
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. Patients’ characteristics at diagnosis Patients underwent a visit 3 months after surgery (Fig. 1 ) evaluating basal and recombinant human TSH-stimulated thyroglobulin (TG) levels, anti-TG antibody (ATG) levels, neck ultrasound (US), whole-body I
Marek Niedziela
Marek Niedziela
Department of Pediatric Endocrinology and Rheumatology, Poznan University of Medical Sciences, Poznan, Poland
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Nelly Sabbaghian
Nelly Sabbaghian
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
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Leanne de Kock
Leanne de Kock
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada
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Department of Human Genetics, McGill University, Montreal, Québec, Canada
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William D. Foulkes
William D. Foulkes
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Québec, Canada
Department of Human Genetics, McGill University, Montreal, Québec, Canada
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Department of Human Genetics, McGill University, Montreal, Québec, Canada
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ultrasonography for the evaluation of thyroid and nonthyroid neck diseases, the incidental discovery of previously unsuspected thyroid nodules/nonpalpable lesions has increased. An intrathyroidal thymus arises due to aberrant thymic migration during embryogenesis
Santiago Tofé
Santiago Tofé
Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain
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Iñaki Argüelles
Iñaki Argüelles
Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain
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Ana Forteza
Ana Forteza
Department of Pathology, University Hospital Son Espases, Palma de Mallorca, Spain
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Cristina Álvarez
Cristina Álvarez
Department of Surgery, Section of Endocrine Surgery, University Hospital Son Espases, Palma de Mallorca, Spain
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Alessandra Repetto
Alessandra Repetto
Department of Nuclear Medicine, University Hospital Son Espases, Palma de Mallorca, Spain
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Luis Masmiquel
Luis Masmiquel
Department of Endocrinology, University Hospital Son Llatzer, Palma de Mallorca, Spain
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Irene Rodríguez
Irene Rodríguez
Department of Endocrinology, University Hospital Son Llatzer, Palma de Mallorca, Spain
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Eladio Losada
Eladio Losada
Department of Endocrinology, Hospital Can Misses, Ibiza, Spain
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Nuria Sukunza
Nuria Sukunza
Department of Endocrinology, Hospital de Manacor, Manacor, Spain
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María Cabrer
María Cabrer
Department of Endocrinology, Hospital Comarcal de Inca, Inca, Spain
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Mildred Sifontes
Mildred Sifontes
Department of Pathology, Hospital Mateu Orfila, Menorca, Spain
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María del Mar del Barrio
María del Mar del Barrio
Department of Pathology, Hospital Mateu Orfila, Menorca, Spain
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Antonia Barceló
Antonia Barceló
Department of Laboratory, University Hospital Son Espases, Palma de Mallorca, Spain
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Álvaro Tofé
Álvaro Tofé
Department of Maxillofacial Surgery, Hospital Puerta del Mar, Cádiz, Spain
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Vicente Pereg
Vicente Pereg
Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain
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-specific MRs in this large cohort of patients with TC. Finally, we have performed an additional analysis to explore the role of changes in the routine management of thyroid nodular disease, that is, performance of neck ultrasound (US) and fine-needle aspiration
