Salman Razvi
Salman Razvi
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Bronia Arnott
Bronia Arnott
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Dawn Teare
Dawn Teare
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Shaun Hiu
Shaun Hiu
Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Nicki O’Brien
Nicki O’Brien
Department of Psychology, Northumbria University, Newcastle upon Tyne, United Kingdom
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Simon H. Pearce
Simon H. Pearce
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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current professional role (consultant endocrinologist or equivalent, trainee endocrinologist, or other clinician). In addition, to explore potential reasons underlying regional differences in treatment decisions of the older person with SCH, we also
Simon P. Mooijaart
Simon P. Mooijaart
Institute for Evidence-Based Medicine in Old Age/IEMO, Leiden, The Netherlands
Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands
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Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands
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Dear Editor, In this letter we would like to emphasize a specific part of the new ETA guideline which was explained in the paper by Pearce et al. [ 1 ], more specifically the part on thyroid hormone supplementation in the oldest old. In
Jesper Karmisholt
Jesper Karmisholt
Department of Medical Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Clinical Institute, Aalborg University, Aalborg, Denmark
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Clinical Institute, Aalborg University, Aalborg, Denmark
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Stig Andersen
Stig Andersen
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
Clinical Institute, Aalborg University, Aalborg, Denmark
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Clinical Institute, Aalborg University, Aalborg, Denmark
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27 Sawin CT , Geller A , Wolf PA , Belanger AJ , Baker E , Bacharach P , et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons . N Engl J Med . 1994 Nov ; 331 ( 19 ): 1249 – 52
Santiago Tofé
Santiago Tofé
Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain
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Iñaki Argüelles
Iñaki Argüelles
Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain
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Ana Forteza
Ana Forteza
Department of Pathology, University Hospital Son Espases, Palma de Mallorca, Spain
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Cristina Álvarez
Cristina Álvarez
Department of Surgery, Section of Endocrine Surgery, University Hospital Son Espases, Palma de Mallorca, Spain
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Alessandra Repetto
Alessandra Repetto
Department of Nuclear Medicine, University Hospital Son Espases, Palma de Mallorca, Spain
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Luis Masmiquel
Luis Masmiquel
Department of Endocrinology, University Hospital Son Llatzer, Palma de Mallorca, Spain
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Irene Rodríguez
Irene Rodríguez
Department of Endocrinology, University Hospital Son Llatzer, Palma de Mallorca, Spain
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Eladio Losada
Eladio Losada
Department of Endocrinology, Hospital Can Misses, Ibiza, Spain
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Nuria Sukunza
Nuria Sukunza
Department of Endocrinology, Hospital de Manacor, Manacor, Spain
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María Cabrer
María Cabrer
Department of Endocrinology, Hospital Comarcal de Inca, Inca, Spain
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Mildred Sifontes
Mildred Sifontes
Department of Pathology, Hospital Mateu Orfila, Menorca, Spain
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María del Mar del Barrio
María del Mar del Barrio
Department of Pathology, Hospital Mateu Orfila, Menorca, Spain
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Antonia Barceló
Antonia Barceló
Department of Laboratory, University Hospital Son Espases, Palma de Mallorca, Spain
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Álvaro Tofé
Álvaro Tofé
Department of Maxillofacial Surgery, Hospital Puerta del Mar, Cádiz, Spain
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Vicente Pereg
Vicente Pereg
Department of Endocrinology, University Hospital Son Espases, Palma de Mallorca, Spain
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is growing faster than any other type of malignancy ( 1 ), regardless of sociodemographic, ethnic, or environmental differences ( 2 ). Conversely, mortality rates (MRs) for TC have decreased or remained stable at 0.5 cases per 100,000 person
Juan Bernal
Juan Bernal
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Maria Jesús Obregon
Maria Jesús Obregon
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Pilar S. Santisteban
Pilar S. Santisteban
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that this control was especially dramatic in the brain. Against the old thinking that the placenta was impermeable to thyroid hormones, she demonstrated that there is a transfer of thyroid hormones from mother to fetus from early gestational stages, and
Yi Pan
Yi Pan
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga
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Kathleen L. Caldwell
Kathleen L. Caldwell
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga
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Yan Li
Yan Li
Joint Program in Survey Methodology, University of Maryland, College Park, Md., USA
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Samuel P. Caudill
Samuel P. Caudill
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga
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Mary E. Mortensen
Mary E. Mortensen
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga
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Amir Makhmudov
Amir Makhmudov
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga
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Robert L. Jones
Robert L. Jones
Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Ga
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6 and older in NHANES survey periods 2001-2002, 2003-2004, 2005-2006 and 2009-2010, as well as in all survey participants aged 6 and older during the cycle 2007-2008. NHANES, conducted by the Centers for Disease Control and Prevention, is a
Lan Wu
Lan Wu
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China
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Salvatore Vaccarella
Salvatore Vaccarella
International Agency for Research on Cancer (IARC/WHO), Lyon, France
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Chen-Yang Feng
Chen-Yang Feng
Information Technology Center, Sun Yat-sen University Cancer Center, Guangzhou, China
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Luigino Dal Maso
Luigino Dal Maso
Unit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy
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Yu Chen
Yu Chen
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China
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Wei-Wei Liu
Wei-Wei Liu
Department of Head and Neck, Sun Yat-sen University Cancer Center, Guangzhou, China
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Miao-Bian Liang
Miao-Bian Liang
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China
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Zike Zhang
Zike Zhang
Department of Laboratory Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
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Jun Yang
Jun Yang
School of Public Health, Guangzhou Medical University, Guangzhou, China
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Su-Mei Cao
Su-Mei Cao
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China
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Mengmeng Li
Mengmeng Li
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China
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between the increasing thyroid cancer incidence and the stable or declining mortality is one of the visible consequences in support of overdiagnosis ( 3 ). Overdiagnosis is a phenomenon that labels a person with a disease or abnormal condition that would
Simon H.S. Pearce
Simon H.S. Pearce
Institute of Genetic Medicine, Newcastle University and Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK;
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Mario Vaisman
Mario Vaisman
Department of Endocrinology, Faculdade de Medicina, UFRJ, Rio de Janeiro, Brazil;
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Jean-Louis Wemeau
Jean-Louis Wemeau
Clinique Endocrinologique Marc Linquette, CHU, Lille, France
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.1300350 28 Sawin CT, Geller A, Wolf PA, Belanger AJ, Baker E, Bacharach P, Wilson PW, Benjamin EJ, D’Agostino RB: Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med 1994;331:1249–1252. 10.1056/NEJM
Else Marie Opsahl
Else Marie Opsahl
Section of Breast and Endocrine Surgery, Department of Oncology, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
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Institute of Clinical Medicine, University of Oslo, Oslo, Norway
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Lars Andreas Akslen
Lars Andreas Akslen
Section for Pathology, Department of Clinical Medicine, Centre for Cancer Biomarkers CCBIO, University of Bergen, Bergen, Norway
Department of Pathology, Haukeland University Hospital Bergen, Bergen, Norway
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Department of Pathology, Haukeland University Hospital Bergen, Bergen, Norway
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Ellen Schlichting
Ellen Schlichting
Section of Breast and Endocrine Surgery, Department of Oncology, Oslo University Hospital, Oslo, Norway
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Turid Aas
Turid Aas
Department of Breast and Endocrine Surgery, Haukeland University Hospital, Bergen, Norway
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Katrin Brauckhoff
Katrin Brauckhoff
Department of Breast and Endocrine Surgery, Haukeland University Hospital, Bergen, Norway
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Anne Irene Hagen
Anne Irene Hagen
Department of Breast and Endocrine Surgery, St. Olavs University Hospital, Trondheim, Norway
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Alf Frimann Rosenlund
Alf Frimann Rosenlund
Section of Breast and Endocrine Surgery, Department of Surgery, University Hospital of North Norway, Tromsø, Norway
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Eva Sigstad
Eva Sigstad
Department of Pathology, Oslo University Hospital, Oslo, Norway
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Krystyna K. Grøholt
Krystyna K. Grøholt
Department of Pathology, Oslo University Hospital, Oslo, Norway
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Lovise Mæhle
Lovise Mæhle
Department of Medical Genetics, Oslo University Hospital, Oslo, Norway
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Lars Fredrik Engebretsen
Lars Fredrik Engebretsen
Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway
Department of Medical Genetics, St. Olavs University Hospital, Trondheim, Norway
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Department of Medical Genetics, St. Olavs University Hospital, Trondheim, Norway
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Lars H. Jørgensen
Lars H. Jørgensen
Department of Thoracic Surgery, Oslo University Hospital, Oslo, Norway
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Jan Erik Varhaug
Jan Erik Varhaug
Department of Clinical Science, University of Bergen, Bergen, Norway
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Trine Bjøro
Trine Bjøro
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway
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Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway
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performed in 27 patients due to locally advanced or disseminated disease, other advanced diseases, or old age in 22 patients. In 5 patients, MTC was diagnosed by autopsy. Those patients were excluded from this study. Fig. 1. Study cohort with
Wilmar M. Wiersinga
Wilmar M. Wiersinga
Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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.1159/000360621 25114879 5 Sawin CT, Geller A, Wolf PA, et al: Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med 1994;331:1249-1252. 10.1056/NEJM199411103311901 7935681 6 Zulewski H, Müller B, Exer
