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carcinomas (PTCs) including papillary thyroid microcarcinomas (PTMCs) [ 1 , 2 ]. For the last several decades, we did not have sufficient knowledge of the biological behavior of PTMCs, and were surprised to find that many of these PTMCs have similar
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Introduction The incidence of papillary thyroid cancer (PTC) has almost doubled over the last three decades mainly due to the higher incidence of papillary thyroid microcarcinoma (MPTC) [ 1 , 2 ]. In Italy, a remarkably high PTC incidence has
Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University Sejong Hospital, Sejong, Republic of Korea
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Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
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Department of Otolaryngology-Head and Neck Surgery, Chungnam National University Hospital, Daejeon, Republic of Korea
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increase in papillary thyroid microcarcinoma (PTMC), defined as papillary thyroid carcinoma less than 1 cm; accordingly, concerns have been raised regarding overdiagnosis ( 6 , 7 ). Another characteristic of thyroid cancer is indolent progression
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shows that surgery can detect features associated with a poor prognosis in adults with a preoperative diagnosis of “nonaggressive papillary microcarcinoma restricted to the thyroid,” and thus potential candidates for AS [ 1 - 5 ]. How often this occurs
Center of Genomic Medicine, Rigshospitalet, Copenhagen University, Copenhagen, Denmark
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Frates et al. [ 7 ] the accumulated predicted value of US characteristics and basic clinical features ranged between 3 and 48%. The papillary thyroid microcarcinoma (PTMC) is a papillary thyroid carcinoma with a size of ≤1 cm. The overall incidence of
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Dear Editor, Recently, Russ et al. [ 1 ] endorsed active surveillance for low-risk papillary microcarcinoma of the thyroid (PMT). It is also reasonable to imagine that, if immediate treatment is not necessary, fine-needle aspiration (FNA) of
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case for all micromedullary tumors. In one study, calcitonin levels were only elevated in tumors larger than 0.5 cm [ 14 ]. In contrast to MTC, the incidence of incidental papillary thyroid microcarcinoma is common, well documented and investigated
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to the progression of papillary microcarcinoma of the thyroid under observation. Thyroid 2014;24:27-34. 10.1089/thy.2013.0367 24001104 40 So YK, Son YI, Hong SD: Subclinical lymph node metastasis in papillary thyroid microcarcinoma: a study of
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[ 1 , 2 , 3 ]. Multifocal papillary thyroid carcinomas (PTC) can be divided into 2 categories depending on the tumor size: multifocal papillary microcarcinoma (all of the lesions sized <1 cm) and multifocal macroscopic papillary thyroid cancer
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Surgery and Physiology, Cardiovascular Research Unit, Faculty of Medicine from the University of Porto, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Institute for Research Innovation in Health, University of Porto, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Department of Surgery and Physiology, Cardiovascular Research Unit, Faculty of Medicine from the University of Porto, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar Universitário de São João, Porto, Portugal
Institute for Research Innovation in Health, University of Porto, Porto, Portugal
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papillary carcinomas, and 1 (5.6%) was NIFTP (non-invasive follicular thyroid neoplasm with papillary-like nuclear features). Of the 10 microcarcinomas, 3 were discovered on preoperatory FNA, 1 discovered by FNA of a cervical lymph node, and 6 were an