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. This further corresponds with the results of good reproducibility and interobserver agreement. Like a previous meta-analysis [ 16 ], the present study demonstrated that sensitivity of both Kw-TIRADS and EU-TIRADS for the diagnosis of thyroid
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initial evaluation and follow-up of thyroid nodules and cancer. In order to enhance the interobserver reproducibility of descriptions and to simplify communication of the results, the ETA task force has issued a new simplified TIRADS, to be called EU
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cytomorphological features seen in AUS/FLUS (follicular lesion of undetermined significance) reporting and concluded that there is marked heterogeneity within the atypia category with resultant questionable reproducibility. Repeat FNA resulted in the
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the adverse effects and limit the resulting additional costs. The value of determining serum parathyroid hormone (PTH) levels as a biological risk marker for hypoPTH occurrence is largely recognized, and the realization of this early assay (at the
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the alanine side chain [ 2 ]. Side chain deamination results in thyroacetic acids, whereas side chain decarboxylation generates the novel class of biologically active metabolites called thyronamines (TAM; see table 1 ). So far, only two
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]. However, the role of RFNA for AUS/FLUS nodules is controversial. First, RFNA also reproduce significant inconclusive results. The rate of repeated AUS/FLUS results by RFNA is estimated to approximately be up to 67% [ 3 , 4 , 5 , 6 ]. Second, RFNA may not
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diagnostic performance of FNA cytology in the setting of indeterminate results has led to the search for diagnostic biomarkers, and several recently introduced molecular tests [ 9 ], such as gene expression classifier (GEC) [ 10 ], gene mutational panel [ 11
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near the thyroid gland in 0.7% (1/140). Discussion Prior to the Bethesda System for Reporting Thyroid Cytopathology, there was no standard classification and no application of reproducible cytological reporting of thyroid nodule FNA results
Department of Oto-Rhino-Laryngology – Head and Neck Surgery, University Hospital Essen, Essen, Germany
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Department of Ophthalmology, University Hospital Essen, Essen, Germany
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of hyperplastic and autoimmune diseases are invaluable investigative tools for complex pathological conditions such as GD and autoimmune thyroiditis [ 5 - 7 ]. We have recently reported the development of a robust and reproducible model of
University of Montpellier I, Sud de France, Montpellier, France
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, surgical indications, surgeons training, number of thyroid surgery centre as well as the morphology of Korean people raise some questions concerning the reproducibility of these remarkable results elsewhere in the world. To date, only 9 reports of