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Sampath Satish Kumar Departments of Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Sheila Fraser Departments of Endocrine Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Andrew Scarsbrook Departments of Radiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Ken MacLennan Leeds Institute of Molecular Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Mark Lansdown Departments of Endocrine Surgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Robert D. Murray Departments of Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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What Is Known about This Topic • Riedel’s thyroiditis is a rare condition of unknown aetiology, characterised by chronic inflammatory invasive fibrosclerosis of the thyroid gland and surrounding structures. Riedel’s thyroiditis is also

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Tumay Ozgur Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Hasan Gokce Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Ihsan Ustun Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Yaldiz Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Mustafa Akin Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Cumali Gokce Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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What Is Known about This Topic • Riedel thyroiditis is a rare disorder. • Riedel thyroiditis has been associated with other thyroid conditions like chronic lymphocytic thyroiditis, hypothyroidism, hyperthyroidism ad anaplastic carcinoma

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Asena Gökçay Canpolat Department of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey

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Murat Cinel Department of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey

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Serpil Dizbay Sak Department of Pathology, School of Medicine, Ankara University, Ankara, Turkey

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Işılay Taşkaldıran Department of Endocrinology and Metabolism, Ankara Training and Research Hospital, Ankara, Turkey

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Hakan Korkmaz Department of Endocrinology and Metabolism, School of Medicine, Süleyman Demirel University, Isparta, Turkey

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Özgür Demir Department of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey

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Reyhan Ersoy Department of Endocrinology and Metabolism, School of Medicine, Yıldırım Beyazıt University, Ankara, Turkey

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Selçuk Dağdelen Department of Endocrinology and Metabolism, School of Medicine, Hacettepe University, Ankara, Turkey

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Dilek Berker Department of Endocrinology and Metabolism, Ankara City Hospital, University of Health Sciences, Ankara, Turkey

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Klara Dalva Department of Haematology, School of Medicine, Ankara University, Ankara, Turkey

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Adile Begüm Bahçecioğlu Mutlu Department of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey

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Murat Faik Erdoğan Department of Endocrinology and Metabolism, School of Medicine, Ankara University, Ankara, Turkey

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Introduction Immunoglobulin G4-related disease (IgG4-RD) is characterized by an immune-mediated fibroinflammatory process that can affect various organs [ 1 ]. Riedel thyroiditis (RT) is a rare form of thyroiditis, which may also occur as part

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Dulani Kottahachchi Department of Endocrinology and Diabetes, The Alfred Hospital, Australia

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Duncan J. Topliss Department of Endocrinology and Diabetes, The Alfred Hospital, Australia
Department of Medicine, Monash University, Melbourne, VIC, Australia

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], retroperitoneal fibrosis [ 4 ], Küttner tumour [ 5 ], and Riedel thyroiditis (RT) [ 6 ]. In 2012 a consensus guideline on the nomenclature of IgG4-RD was released, which brought together the disparate organ diseases into 1 disease spectrum [ 1 ]. Figure 1

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Anthony P. Weetman Department of Human Metabolism, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK

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. Hashimoto carefully distinguished this condition from Riedel thyroiditis and speculated whether or not it was related to Mikulicz disease, which was remarkably prescient: we now know that patients with this entity, better known as Sjögren syndrome, have a

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Christophe Ghys Department of Endocrinology, Universitair Ziekenhuis Brussel, Belgium

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Michel Depierreux Departments of Pathology, Brussels, Belgium

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Elçin Ozalp Departments of Nuclear Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium

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Brigitte Velkeniers Department of Endocrinology, Universitair Ziekenhuis Brussel, Belgium

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What Is Known about This Topic? • Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized fibroinflammatory process defined by a dense lymphoplasmacytic infiltrate rich in IgG4. Riedel's thyroiditis and a subclass of sclerosing

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Eijun Nishihara Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Nobuyuki Amino Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Takumi Kudo Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Kazuyoshi Kohsaka Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Shuji Fukata Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsushige Nishikawa Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Hirotoshi Nakamura Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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treatment . Intern Med . 2008 ; 47 ( 8 ): 725 – 9 . 10.2169/internalmedicine.47.0740 18421188 0918-2918 2 Shrestha RT , Hennessey J . Acute and Subacute, and Riedel’s Thyroiditis . In: Feingold KR , Anawalt B , Boyce A , Chrousos G

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Akshay Khatri Division of Infectious Diseases, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, New York, USA

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Esti Charlap Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Great Neck, New York, USA

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Angela Kim Division of Infectious Diseases, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, New York, USA

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. 577 . 8 Shrestha RT , Hennessey J . Acute and subacute, and Riedel’s thyroiditis. [Updated 2015 Dec 8] . In: Feingold KR , Anawalt B , Boyce A , Chrousos G , de Herder WW , Dungan K , , editors. Endotext [Internet] . South

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José I. López Department of Pathology, Cruces University Hospital, BioCruces Research Institute, University of the Basque Country, Barakaldo

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Rosa Zabala Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain

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José Luís del Cura Department of Radiology, Basurto University Hospital, University of the Basque Country, Bilbao, Spain

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. Depending on the course of the disease, there is a greater or lesser degree of stromal fibrosis. Notably, it can be very clear in the fibrosing variant of Hashimoto's thyroiditis and in the very rare condition Riedel's thyroiditis. Vigorous physical

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