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images were viewed with the confocal microscope Zeiss ELYRA PS.1 LSM710. Representative examples are shown (n = 4). Discussion Here we have shown sex-dependent liver expression of the TJ protein claudin-1 and distinct alterations of
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(gastrocnemius muscle, BAT and WAT) in Tbl1xr1 Y446C/Y446C mice compared to age- and sex-matched Tbl1xr1 +/+ mice. Relative RNA expression is measured by qPCR analysis. White bars indicate Tbl1xr1 +/+ and black bars indicate Tbl1xr1 Y446C/Y446C
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sexes. When analyzed in the whole group, a positive correlation was found between ER-α expression and tumor size, a finding seemingly in line with the trend reported in the literature [ 34 ]. Unexpectedly, however, the above correlation could not be
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(VDR), is expressed in many tissues including benign and malignant thyroid tissue [ 2 , 3 ]. 1,25(OH) 2 D 3 concentration dependently inhibits TSH-stimulated iodide uptake in rat thyroid follicular (FRTL-5) cells [ 4 ]. We and others have shown that
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-associated genetic variants seemed to differentially modulate CAPZB expression in a tissue-dependent manner, as shown in Fig. 3A: whereas a TSH-associated genetic signal upstream of CAPZB also underlies differential CAPZB expression in the thyroid, another
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]. In contrast, T3-stimulated Ucp1 expression in inguinal WAT is dependent on TRβ [ 20 ]. Heat production in BAT is stimulated by the SNS but has an absolute requirement for TH. Thus, local T3 and the catecholamine norepinephrine (NE) released from
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CEINGE – Biotecnologie Avanzate Scarl, Naples, Italy
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Endocrinology 2011 331 143 – 149 . ( https://doi.org/10.1016/j.mce.2010.09.004 ) 68 Duarte-Guterman P Ryan MJ & Trudeau VL . Developmental expression of sex steroid-and thyroid hormone-related genes and their regulation by triiodothyronine in the
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China
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Supplementary Table 5. After adjusted for age, sex, BMI, and the time of sample collection, the expression of BMAL1 was negatively correlated with the levels of TPOAb ( β = −0.526, P < 0.001) and IL-2 ( β = −0.417, P = 0.004); the expression of PER2
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between cones depends on the expression of the visual pigments expressed in cone photoreceptors which are made up of a large protein component called opsin [ 1 ]. Although most mammals including mice differentially express M and S opsins for response to
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: Hormone-dependent regulation of intercellular adhesion molecule-1 gene expression: cloning and analysis of 5′-regulatory region of rat intercellular adhesion molecule-1 gene in FRTL-5 rat thyroid cells. Thyroid 1999;9:601-612. 10411124 18 Kim H