( 11 ) and lower compared to our currently used Tg IRMA. This study has two aims. Our first aim is to compare the Tg-IRMA and Tg-LC-MS/MS analytically in the presence of TgAbs. Our secondary aim is to compare the clinical interpretation based on the
Bernadette L Dekker, Anouk N A van der Horst-Schrivers, Adrienne H Brouwers, Christopher M Shuford, Ido P Kema, Anneke C Muller Kobold, and Thera P Links
Mathieu Spaas, Brigitte Decallonne, Annouschka Laenen, Jaak Billen, and Sandra Nuyts
immunoradiometric assay kit (Thyroglobuline IRMA®; CISbio) was used for serum Tg measurement with a functional sensitivity level of 0.7 ng/mL. Automated anti-Tg Ab assays (Elecsys®; Roche diagnostics) were used to detect the presence of anti-Tg antibodies. All
Sylvie Hiéronimus, Patricia Ferrari, Jocelyn Gal, Frédéric Berthier, Stéphane Azoulay, André Bongain, Patrick Fénichel, and Françoise Brucker-Davis
IRMA, Cis bio International, Gif-sur-Yvette, France). fT4, fT3, total T4, TSH and anti-Tg antibodies were measured by chemiluminescence (ADVIA Centaur, Siemens Healthcare Diagnostics, France), while rT3 was measured by radioimmunoassay (Pasteur
Françoise Brucker-Davis, Patricia Panaïa-Ferrari, Jocelyn Gal, Patrick Fénichel, and Sylvie Hiéronimus
iodine deficiency (ID), with special attention to women of childbearing age [ 3 , 8 , 9 ]. One important issue is to determine to what extent the drop in maternal FT4 is caused by insufficient iodine intake. Based on maternal thyroglobulin (Tg) levels and
Zohar Steinberg Ben-Zeev, Marina Peniakov, Clari Felszer, Scott A Weiner, Avishay Lahad, Shlomo Almashanu, and Yardena Tenenbaum Rakover
for FT4, 10–20 pmol/L. Normal references for the first week of life in our laboratory were 0.4–10 mIU/L for TSH and 10–26.8 pmol/L for FT4. Tg and TPO antibodies (Ab) were measured by direct automated chemiluminescent IRMA using an Immulite 2000