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Bernadette L Dekker, Anouk N A van der Horst-Schrivers, Adrienne H Brouwers, Christopher M Shuford, Ido P Kema, Anneke C Muller Kobold, and Thera P Links

-tandem mass spectrometry (LC-MS/MS), which digests Tg into peptides for analytical measurement, disrupting the interfering TgAbs ( 8 ). However, Tg-LC-MS/MS assays studied to date are hampered by a lack of sensitivity compared to Tg immunoassays ( 1 , 2 , 9

Open access

Eijun Nishihara, Yoshitaka Hobo, Akira Miyauchi, Yasuhiro Ito, Miyoko Higuchi, Mitsuyoshi Hirokawa, Mitsuru Ito, Shuji Fukata, Mitsushige Nishikawa, and Takashi Akamizu

-tandem mass spectrometry (LC-MS/MS) for Tg quantification has emerged as an alternative method that may not be influenced by TgAb. This method is based on specific peptide quantitation following tryptic digestion of all proteins, including TgAb and

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Lisbeth Harder, Nancy Schanze, Assel Sarsenbayeva, Franziska Kugel, Josef Köhrle, Lutz Schomburg, Jens Mittag, and Carolin S. Hoefig

TAM Analysis in Liver Hepatic THs and TAMs were extracted from 80 mg of mouse liver as previously described [ 2 , 13 ] followed by liquid chromatography tandem-mass spectrometry (LC-MS/MS) analysis as published [ 14 ]. A brief description of the

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Françoise Brucker-Davis, Patricia Panaïa-Ferrari, Jocelyn Gal, Patrick Fénichel, and Sylvie Hiéronimus

.10.042 19114271 24 Anckaert E, Poppe K, Van Uytfanghe K, Schiettecatte J, Foulon W, Thienpont LM: FT4 immunoassays may display a pattern during pregnancy similar to the dialysis ID-LC/tandem MS candidate reference measurement procedure in spite of

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L.C. Cardoso-Weide, R.C. Cardoso-Penha, M.W. Costa, A.C.F. Ferreira, D.P. Carvalho, and P.S. Santisteban

explores DuOx regulation by TSH, cAMP and CREB (cAMP response element-binding protein), as these factors also regulate TPO (thyroperoxidase) and Tg (thyroglobulin) expression [ 13 ]. Furthermore, as insulin and insulin-like growth factor 1 (IGF-1) have

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Carles Zafon, Juan J. Díez, Juan C. Galofré, and David S. Cooper

role of TKIs in the management of advanced thyroid cancer, several concerns remain to be addressed (Fig. 2 ). Fig. 2 Topics that remain to be elucidated in the treatment of thyroid cancer with TKIs. TKI, tyrosine kinase inhibitor; Tg

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Irene Campi, Maura Agostini, Federica Marelli, Tiziana de Filippis, Beatriz Romartinez-Alonso, Odelia Rajanayagam, Giuditta Rurale, Ilaria Gentile, Federica Spagnolo, Massimiliano Andreasi, Francesco Ferraù, Salvatore Cannavò, Laura Fugazzola, Krishna V. Chatterjee, and Luca Persani

better consistency may be found by ultrafiltration LC-MS/MS, which is less influenced by the transport proteins [ 16 ]. Interestingly, in this family there was a large variability in the clinical manifestations of RTHβ, being the proband more severely

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Dagmar Führer, Klaudia Brix, and Heike Biebermann

analysis of TH metabolites in cell culture samples using LC-MS/MS. Their approach is a prerequisite for comprehensive analysis of TH and TH derivatives in more complex biological samples such as blood or tissues of humans and/or animal models. In addition

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Tiziana de Filippis, Federica Marelli, Maria Cristina Vigone, Marianna Di Frenna, Giovanna Weber, and Luca Persani

significant vs. 125 ng WT-NKX2-1 + 125 ng empty vector. Luciferase Assay The luciferase activity detected in cells transiently transfected with 250 ng of WT- NKX2-1 cDNA is about fourfold higher over baseline, whereas no activation of the TG

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Yuan Li, Chenxu Zhao, Keli Zhao, Nan Yu, Yan Li, Yang Yu, Yang Zhang, Zhijing Song, Youyuan Huang, Guizhi Lu, Ying Gao, Junqing Zhang, and Xiaohui Guo

: an LC/MS characterization . Anal Biochem . 2006 Feb ; 349 ( 2 ): 197 – 207 . 10.1016/j.ab.2005.11.012 16360109 0003-2697 25 Parekh RB , Dwek RA , Sutton BJ , Fernandes DL , Leung A , Stanworth D , et al. Association of