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Marta Amaro da Silveira Duval, André Borsatto Zanella, Ana Patrícia Cristo, Carlo Sasso Faccin, Marcia Silva Graudenz, and Ana Luiza Maia

cellularity or unsatisfying sampling precludes diagnosis in up to 20% of specimens, depending on the cytopathologist’s experience and skill [ 9 , 10 ]. Measurement of thyroglobulin in the washout of fine needle aspiration (FNA-Tg) has been used as an

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Mathieu Spaas, Brigitte Decallonne, Annouschka Laenen, Jaak Billen, and Sandra Nuyts

normal thyroid tissue; secondly, RRA allows for serum thyroglobulin (Tg) to be used as a specific tumor marker and increases sensitivity of diagnostic whole-body iodine scintigraphy (WBS) in the follow-up, allowing early detection of recurrent or

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Cláudia C.D. Nakabashi, Teresa S. Kasamatsu, Felipe Crispim, Claudia A. Yamazaki, Cléber P. Camacho, Danielle M. Andreoni, Rosalia P. Padovani, Elza S. Ikejiri, Maria C.O.M. Mamone, Flávia C. Aldighieri, Jairo Wagner, Jairo T. Hidal, José G.H. Vieira, Rosa P.M. Biscolla, and Rui M.B. Maciel

a nonsignificant risk of recurrence from undergoing unnecessary investigations and identify those individuals with a higher risk who merit closer follow-up [ 6 , 7 ]. The measurement of serum thyroglobulin (Tg) levels is one of the most important

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Birte Nygaard, Jens Bentzen, Peter Laurberg, Susanne Møller Pedersen, Lars Bastholt, Aase Handberg, Carsten Rytter, Christian Godballe, and Jens Faber

]. International guidelines [ 4 , 5 ] suggest a differentiation of patients into low and high risk, low risk patients having a life expectancy close to that of the background population. Serum thyroglobulin (s-Tg) is used as a tumor marker during follow-up after

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Eftychia Koukkou, Ioannis Ilias, Irene Mamalis, Georgios G. Adonakis, and Kostas B. Markou

UIC is highly influenced by recent iodine intake, it can only be used to determine iodine status for populations and not for individuals [ 9 ]. Serum thyroglobulin (Tg) may also be a suitable marker of the current iodine status in a population

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Sylvie Hiéronimus, Patricia Ferrari, Jocelyn Gal, Frédéric Berthier, Stéphane Azoulay, André Bongain, Patrick Fénichel, and Françoise Brucker-Davis

level [ 1 , 2 ], serum thyroglobulin (Tg) has been proposed as a marker of ID [ 3 ], including in newborns [ 4 , 5 ]. Maternal iodine supplementation has been shown to improve maternal and cord blood (CB) thyroid tests in areas of moderate and severe ID

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Carolina C.P.S. Janovsky, Rui M.B. Maciel, Cleber P. Camacho, Rosalia P. Padovani, Claudia C. Nakabashi, Ji H. Yang, Eduardo Z. Malouf, Elza S. Ikejiri, M. Conceição O.C. Mamone, Jairo Wagner, Danielle M. Andreoni, and Rosa Paula M. Biscolla

has additional benefits, such as postdose RRA scanning in postsurgical staging and improving the sensitivity of serum thyroglobulin (Tg) during follow-up [ 4 , 8 ]. However, more recent guidelines recommend a more judicious use of RRA in low

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Françoise Brucker-Davis, Patricia Panaïa-Ferrari, Jocelyn Gal, Patrick Fénichel, and Sylvie Hiéronimus

iodine deficiency (ID), with special attention to women of childbearing age [ 3 , 8 , 9 ]. One important issue is to determine to what extent the drop in maternal FT4 is caused by insufficient iodine intake. Based on maternal thyroglobulin (Tg) levels and

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Till Ittermann, Adrian Richter, Martin Junge, Matthias Nauck, Astrid Petersmann, Clemens Jürgens, Harald Below, Carsten Oliver Schmidt, and Henry Völzke

[ 3 - 5 ]. Intra- and interindividual biological variations for laboratory blood markers including thyroid-stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3), and thyroglobulin are reported in Ricós’s table [ 6 ]. Observer and

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Pedro Weslley Rosario, Gabriela Franco Mourão, and Maria Regina Calsolari

Chemiluminescent assays were used for the measurement of Tg (Access Thyroglobulin Assay, Beckman Coulter, Fullerton, CA, USA [functional sensitivity (FS) in our laboratory of 0.1 ng/ml]) and TgAb (Immulite 2000, Diagnostic Products Corporation, Los Angeles, CA, USA