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thyroidectomy; PTC, papillary thyroid carcinoma; RNM, regional nodal metastases; RRA, radioiodine remnant ablation; Categorical variables are presented as number (%); a Kruskal–Wallis test P -value; b Chi-square test P -value. Details of the
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international literature, including many guidelines ( 6 , 7 , 8 ), as the minimum level of TSH stimulation for radioiodine therapy including thyroid remnant ablation. However, there is no definite evidence yet that TSH level ≥ 30 mU/L is necessary for
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Introduction Remnant ablation is a traditional procedure that is usually performed after total thyroidectomy in patients with differentiated thyroid cancer (DTC) tumors >1 cm in diameter [ 1 , 2 ]. Numerous studies have confirmed that
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
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follow-up care [ 2 , 7 , 8 ]. The treatment of differentiated thyroid cancer usually consists of total thyroidectomy (TT) and radioiodine remnant ablation (RRA) [ 4 , 8 ]. The rationale for the use of RRA comprises: remnant ablation, to facilitate the
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131 I. The aim of postsurgical ablation of the thyroid remnant with RAI is to facilitate the early detection of recurrence based on serum thyroglobulin (Tg) measurement and RAI whole body scan. In addition, RAI ablation may represent an adjuvant
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remove the primary tumour and thyroid tissue to facilitate post-operative remnant ablation with radioactive iodine-131 (RAI). The role of RAI is twofold: firstly to ablate the residual normal thyroid remaining after total thyroidectomy, thus facilitating
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not be indicated [ 7 , 8 ], and recent phase III trials have demonstrated equivalent rates of thyroid remnant ablation with 30 versus 100 mCi doses of RAI [ 9 , 10 ], practice patterns remain highly variable by individual practitioner [ 11 ]. The
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Introduction Until a few years ago, the standard therapy of well-differentiated thyroid cancer (DTC) consisted of total or near total thyroidectomy followed by radioiodine (RAI) remnant ablation (RRA) and TSH suppressive levothyroxine (LT4
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many patients undergo radioiodine remnant ablation (RRA) to eliminate the residual normal thyroid tissue after total thyroidectomy (TT) or near TT (NTT). Previous works [ 3 - 5 ] have shown that a low dose of 131-I is as effective as a high dose for
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Practice for the Diagnosis and Management of Thyroid Nodules. Endocr Pract 2010;16:1-43. 10.4158/10024.GL 20497938 22 Lamartina L, Durante C, Filetti S, Cooper DS: Low-risk differentiated thyroid cancer and radioiodine remnant ablation: a systematic