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Henry Völzke, Iris Erlund, Alicja Hubalewska-Dydejczyk, Till Ittermann, Robin P. Peeters, Margaret Rayman, Monika Buchberger, Uwe Siebert, Betina H. Thuesen, Michael B. Zimmermann, Stefan Grünert, and John H. Lazarus

, it is essential for decision makers systematically to evaluate benefits, potential harms and cost-effectiveness of prevention strategies. EUthyroid has developed a decision-analytic model [ 15 ] to evaluate the long-term effectiveness and cost

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Cléber P. Camacho, Susan C. Lindsey, Teresa S. Kasamatsu, Alberto L. Machado, João Roberto M. Martins, Rosa Paula M. Biscolla, Magnus R. Dias da Silva, José Gilberto H. Vieira, and Rui M.B. Maciel

, Fracassi S, Bombardieri E: Evaluation of circulating calcitonin: analytical aspects. Tumori 2003;89:566-568. 14870789 15 Niccoli P, Brunet P, Roubicek C, Roux F, Baudin E, Lejeune PJ, Berland Y, Conte-Devolx B: Abnormal calcitonin basal levels and

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Heleen I Jansen, Antonius E van Herwaarden, Henk J Huijgen, Rebecca C Painter, Jacquelien J Hillebrand, Anita Boelen, and Annemieke C Heijboer

-binding globulin (TBG), 10% to transthyretin and 12% to albumin, while only 0.02% is circulating unbound fT4 ( 9 , 10 ). Serum fT4 is commonly measured using automated immunoassays (IAs) and this measurement is notorious for its analytical challenges because of

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Bernadette L Dekker, Anouk N A van der Horst-Schrivers, Adrienne H Brouwers, Christopher M Shuford, Ido P Kema, Anneke C Muller Kobold, and Thera P Links

-LC-MS/MS Passing-Bablok regression analysis was performed on samples obtained during initial therapy and follow-up (stimulated and unstimulated) for the analytical evaluation. In the 304 samples with lower titer TgAbs (<10 U/mL), the Passing-Bablok regression

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Federica D’Aurizio, Alessia Biasotto, Claudia Cipri, Franco Grimaldi, Jessica Zucco, Stefania Marzinotto, Francesco Curcio, and Salvatore Benvenga

with the others ( 4 ). In such cases, analytical interferences should be investigated in order to avoid unnecessary further diagnostic procedures and/or treatments ( 5 ). In fact, despite numerous advances in immunoassay technology, thyroid hormone

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J L Reverter, L Ferrer-Estopiñan, F Vázquez, S Ballesta, S Batule, A Perez-Montes de Oca, C Puig-Jové, and M Puig-Domingo

assessed the performance of CAD systems in the evaluation of thyroid lesions and concluded that diagnostic performance is comparable to that of experienced observers ( 7 , 8 , 9 , 10 ). In order to maximize the advantages of a CAD system, it is important

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Jesper Karmisholt and Stig Andersen

an L-T4 substitution treatment trial, be evaluated, and continue treatment if symptoms subside [ 8 , 9 ]. Patients in the spectrum from subclinical to overt and severe hypothyroidism can experience a plethora of different symptoms also reported by

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Daniel Rathmann, Eddy Rijntjes, Julika Lietzow, and Josef Köhrle

if the full spectrum of the TH and TAM family is of analytical interest. Technical advances in HPLC liquid chromatography and its subsequent combination with tandem mass spectrometry (LC-MS/MS) provided a highly sensitive method to measure part - most

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Alessia Cozzolino, Tiziana Filardi, Ilaria Simonelli, Giorgio Grani, Camilla Virili, Ilaria Stramazzo, Maria Giulia Santaguida, Pietro Locantore, Massimo Maurici, Daniele Gianfrilli, Andrea M Isidori, Cosimo Durante, Carlotta Pozza, and on behalf of TALENT Group

, thyroid nodules in pediatric patients require a careful evaluation. According to the 2015 American Thyroid Association (ATA) Guidelines on Pediatric Thyroid nodules and Differentiated Thyroid Cancer, the evaluation and treatment of thyroid nodules in

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Ralf Paschke, Silvia Cantara, Anna Crescenzi, Barbara Jarzab, Thomas J. Musholt, and Manuel Sobrinho Simoes

evaluation of various molecular diagnostic tests that contribute to optimal patient care. This source suffers, however, from a large variability of sampling and processing. Cytopathology laboratories utilize numerous different methods to obtain and process