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Renaud Ciappuccini Department of Nuclear Medicine and Thyroid Unit, François Baclesse Cancer Centre, Caen, France
INSERM 1086 ANTICIPE, Caen University, Caen, France

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Virginie Saguet-Rysanek Department of Pathology, François Baclesse Cancer Centre, Caen, France

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Marine Dorbeau Department of Pathology, François Baclesse Cancer Centre, Caen, France

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Justine Lequesne Department of Clinical Research, François Baclesse Cancer Centre, Caen, France

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Camille Linard Department of Pathology, François Baclesse Cancer Centre, Caen, France

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Sophie Lefevre-Arbogast Department of Clinical Research, François Baclesse Cancer Centre, Caen, France

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Bénédicte Clarisse Department of Clinical Research, François Baclesse Cancer Centre, Caen, France

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Stéphane Bardet Department of Nuclear Medicine and Thyroid Unit, François Baclesse Cancer Centre, Caen, France

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prostate cancer and were related to chronic autoimmune thyroiditis (CAT) ( 4 , 5 ). Diffuse thyroid uptake is also a well-known pattern in patients with CAT on 18 F-Fluorodeoxyglucose ( 18 FDG) PET/CT ( 6 , 7 ). Although some authors showed that thyroid

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Anthony P. Weetman Department of Human Metabolism, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK

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, Hashimoto thyroiditis has become the archetype of autoimmune destructive disorders and autoantibody production. This lecture honours Professor Aldo Pinchera, who has made many important contributions to our understanding of thyroid autoimmunity; remarkably

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Jinrong Fu Department of Endocrinology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Zihao Fan Department of Geriatrics, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

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Liang He Department of Thyroid Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China

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Qian Liu Department of Endocrinology and Metabolism, Jilin Cancer Hospital, Changchun, Jilin, China

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He Liu Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Yushu Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Haixia Guan Department of Endocrinology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

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Introduction Autoimmune thyroiditis (AIT), also referred to as Hashimoto’s thyroiditis (HT) or chronic lymphocytic thyroiditis, is a common autoimmune disorder with a prevalence of 0.3–1.5 cases per 1000 subjects per year ( 1 ). AIT is

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Roberto Negro Division of Endocrinology, ‘V. Fazzi' Hospital, Lecce

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria ‘S. Maria della Misericordia', Udine

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Claudio Marcocci Department of Clinical and Experimental Medicine, University of Pisa, Pisa

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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;87:370-378. 18258627 16 Winther KH, Watt T, Bjørner JB, Cramon P, Feldt-Rasmussen U, Gluud C, Gram J, Groenvold M, Hegedüs L, Knudsen N, Rasmussen ÅK, Bonnema SJ: The chronic autoimmune thyroiditis quality of life selenium trial (CATALYST): study protocol for a

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Roberto Negro Division of Endocrinology, “V. Fazzi” Hospital, Lecce, Italy

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Roberto Attanasio Endocrinology Service, Galeazzi Institute IRCCS, Milan, Italy

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Enrico Papini Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Rinaldo Guglielmi Department of Endocrinology, Regina Apostolorum Hospital, Albano Laziale, Italy

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Franco Grimaldi Endocrinology and Metabolic Disease Unit, Azienda Ospedaliero-Universitaria “S. Maria della Misericordia”, Udine, Italy

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Vincenzo Toscano Endocrinology, Department of Clinical and Molecular Medicine, Sant’Andrea Hospital, Sapienza University of Rome, Roma, Italy

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Dan Alexandru  Niculescu Department of Endocrinology, Carol Davila University of Medicine of Pharmacy, Bucharest, Romania

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Diana Loreta  Paun Department of Endocrinology, Carol Davila University of Medicine of Pharmacy, Bucharest, Romania

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Catalina Poiana Department of Endocrinology, Carol Davila University of Medicine of Pharmacy, Bucharest, Romania

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increase the LT4 dosage by 30% both in postsurgical and autoimmune hypothyroidism ( p = ns; Fig.  3 ). When the hypothyroid pregnant patient is on replacement with LT4, two-thirds would like to keep TSH < 2.5 mIU/L ( p < 0.01; Fig.  4 ). Fig. 3

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Giovanni de Gennaro Department of Clinical and Experimental Medicine, Endocrinology Unit I, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Paolo Vitti Department of Clinical and Experimental Medicine, Endocrinology Unit I, University of Pisa and University Hospital of Pisa, Pisa, Italy

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Michele Marinò Department of Clinical and Experimental Medicine, Endocrinology Unit I, University of Pisa and University Hospital of Pisa, Pisa, Italy

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for a familial history of autoimmune thyroiditis. He complained of mild asthenia. His brother was affected by OCA and autoimmune thyroiditis. The physical examination revealed the presence of fair skin, platinum white hair, hypopigmentation of the iris

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Eijun Nishihara Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Nobuyuki Amino Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Takumi Kudo Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Kazuyoshi Kohsaka Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Shuji Fukata Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsushige Nishikawa Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Hirotoshi Nakamura Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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’s thyroiditis [ 25 ], suggesting that TgAb produced in acute thyroid destruction is not similar to that produced in a chronic autoimmune reaction, but represents a nonspecific response to the release of thyroid antigens. Table 3. Reported frequency of

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Christophe Ghys Department of Endocrinology, Universitair Ziekenhuis Brussel, Belgium

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Michel Depierreux Departments of Pathology, Brussels, Belgium

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Elçin Ozalp Departments of Nuclear Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium

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Brigitte Velkeniers Department of Endocrinology, Universitair Ziekenhuis Brussel, Belgium

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-positive plasmacytic cells in the involved organs. The main organs which can be affected are the pancreas, bile ducts, salivary glands, lymph nodes and thyroid. Recently, a subsection of Hashimoto's autoimmune thyroiditis was described, IgG4 thyroiditis

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Wolfgang J. Schnedl Practice for General Internal Medicine, Bruck/Mur

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Siroos Mirzaei Department of Nuclear Medicine, Wilhelminenspital, Vienna

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Sandra J. Wallner-Liebmann Institute of Pathophysiology, Centre for Molecular Medicine, Medical University of Graz

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Erwin Tafeit Institute of Physiological Chemistry, Centre of Physiological Medicine, Medical University of Graz

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Harald Mangge Clinical Institute of Medical and Chemical Laboratory Diagnosis, Medical University of Graz

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Robert Krause Departments of Internal Medicine, Medical University of Graz, Graz, Austria

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Rainer W. Lipp Radiology, Medical University of Graz, Graz, Austria

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-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothyroxine. Thyroid 2008;18:755-760. 10.1089/thy.2008.0008 18631004 12 Chen PL, Wang PY, Hsu HY: Reversible

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Steen J. Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Kristian H. Winther Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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antibodies (TPOAb) in autoimmune thyroiditis [ 6 , 7 ]. Accepting that chronic autoimmune thyroid diseases are multifactorial diseases, and that environmental triggers are key components in their etiology [ 8 ], it is no surprise that Se deficiency has come

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