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Giacomo Sturniolo Department of Human Pathology of the Adult and Developmental Age “G. Barresi”

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Carles Zafon Department of Endocrinology, Diabetes, and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR)

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Mariacarla Moleti Department of Experimental Medicine, University of Messina, Messina, Italy

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Josep Castellví Department of Pathology, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain

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Francesco Vermiglio Department of Experimental Medicine, University of Messina, Messina, Italy

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Jordi Mesa Department of Endocrinology, Diabetes, and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR)

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several studies have investigated the expression of estrogen receptor (ER) subtypes in thyroid cancers. However, results are not consistent yet, likely because of the existence of confounding factors in the populations selected [ 15 , 16 ]. The purpose

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000452488
Volume/Issue:
Volume 5: Issue 4
Free access
Julia Ramalho Amalio da Silva Breder Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Paulo Alonso Garcia Alves Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Mario Lucio Araújo Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Barbara Pires Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Priscila Valverde Pathology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Daniel Alves Bulzico Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Fernanda Andrade Accioly Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Rossana Corbo Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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Mario Vaisman Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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Fernanda Vaisman Endocrinology Department, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Endocrinology Department, Instituto Nacional do Cancer do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

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demonstrated the presence of estrogen receptor (ER) in thyroid tumor cells in adults ( 11 , 12 , 13 , 14 , 15 ). In many studies, ERα positivity has been associated with larger primary tumor size, suggesting that estrogen may act as a growth factor in

Article Type:
Research Article
Collections:
Pediatric thyroid diseases
DOI:
https://doi.org/10.1530/ETJ-21-0090
Volume/Issue:
Volume 11: Issue 2
Open access
Sara Donato Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal

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Helder Simões Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal
Unidade de Investigação em Patobiologia Molecular, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal

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pregnancy may represent a stimulus for DTC growth in patients with structural or biochemical evidence of disease [ 8 ], possibly due to the high levels of estrogen that occur during that physiological state, which can bind to receptors present in cancer

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000512735
Volume/Issue:
Volume 10: Issue 6
Free access
Sepehr Torabinejad Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy

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Caterina Miro Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy

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Biagio Barone Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II

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Ciro Imbimbo Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II

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Felice Crocetto Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II

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Monica Dentice Department of Clinical Medicine and Surgery, University of Naples ’Federico II’, Naples, Italy
CEINGE – Biotecnologie Avanzate Scarl, Naples, Italy

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RGGTCA (R is a purine). Based on their mode of action, they can be subdivided into four different sub-categories: (i) Type I receptors, comprising the AR, the estrogen receptor (ER), and the progesterone receptor (PR), are anchored in the cytoplasm by

Article Type:
Review Article
Collections:
Thyroid hormone action
DOI:
https://doi.org/10.1530/ETJ-22-0228
Volume/Issue:
Volume 12: Issue 3
Open access
Bharath Bachimanchi Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Suresh Vaikkakara Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Alok Sachan Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Ganji Praveen Kumar Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Ashok Venkatanarasu Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Palaparti Sai Krishna Chaitanya Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Bekkem Sreedivya Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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Ravi Poojari Department of Endocrinology & Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

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estrogen (< 73.42 pmol/L) levels. These 5 had higher TSH (> 100 vs. 78.8 mIU/L in women with normal estrogen; p = 0.036). PRL was higher in the hypoestrogenic women, while both the gonadotropins (LH and FSH) were lower (Table 2 ). Table 2

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000495563
Volume/Issue:
Volume 8: Issue 3
Free access
Joachim M. Weitzel Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), FBN Dummerstorf, Dummerstorf, Germany

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. Biochem J 2009;419:167-176. 10.1042/BJ20081556 19067653 23 Wilson BJ, Tremblay AM, Deblois G, Sylvain-Drolet G, Giguere V: An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha. Mol Endocrinol 2010

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000447232
Volume/Issue:
Volume 5: Issue 3
Free access
Denise Zwanziger Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Helena Rakov Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Kathrin Engels Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Lars C. Moeller Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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Dagmar Führer Department of Endocrinology and Metabolism and Division of Laboratory Research, University Hospital Essen, Essen, Germany

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-1 liver expression with different thyroid states, a possible interaction between estradiol and TH may be involved. These seems more likely when it is considered that both receptors - THRs and estrogen - belong to the superfamily of nuclear receptors

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000431316
Volume/Issue:
Volume 4: Issue 1_Suppl
Free access
R. Burns UCD School of Medicine and Medical Science, University College Dublin

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C. O'Herlihy UCD School of Medicine and Medical Science, University College Dublin
National Maternity Hospital, Dublin, Ireland

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P.P.A. Smyth UCD School of Medicine and Medical Science, University College Dublin

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of estrogen, receptors in the developing human placenta. Horm Metab Res 1997;29:604-610. 10.1055/s-2007-979109 9497895 33 Shanker YG, Rao AJ: Progesterone receptor expression in the human placenta. Mol Hum Reprod 1999;5:481-486. 10.1093/molehr

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000356847
Volume/Issue:
Volume 2: Issue 4
Free access
Thea Riis Department of Endocrinology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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Thomas Heiberg Brix Department of Endocrinology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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Lars Folkestad Department of Endocrinology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark

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hormones induced human lung cancer cell proliferation via crosstalk between integrin αvβ3 and estrogen receptor alpha. In a study in mice, thyroxine enhanced the weight of Lewis’ carcinoma and angiogenesis, but this required the activation of integrin αvβ3

Article Type:
Research Article
Collections:
Hyperthyroidism and thyrotoxicosis
DOI:
https://doi.org/10.1530/ETJ-23-0181
Volume/Issue:
Volume 13: Issue 2
Open access
Luca Persani Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Georg Brabant Experimental and Clinical Endocrinology Medical Clinic I – University of Lübeck, Lübeck, Germany

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Mehul Dattani Genetics and Genomic Medicine Programme, UCL GOS Institute of Child Health, London, United Kingdom

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Marco Bonomi Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Division of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Ulla Feldt-Rasmussen Department of Medical Endocrinology and Metabolism, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

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Eric Fliers Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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Annette Gruters Department for Pediatric Endocrinology and Diabetes, Charité University Medicine, Berlin, Germany
University Hospital Heidelberg, Heidelberg, Germany

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Dominique Maiter Department of Endocrinology and Nutrition, UCL Cliniques Saint-Luc, Brussels, Belgium

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Nadia Schoenmakers University of Cambridge Metabolic Research Laboratories, Wellcome Trust-Medical Research Council Institute of Metabolic Science, Addenbrooke’s Hospital and National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, United Kingdom

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A.S. Paul van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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with recombinant human growth hormone (rhGH) or estrogen (see [ 1 ]) (Recommendation 8) as well as in those receiving particular drugs (Recommendation 9), in particular rexinoids (like bexarotene, an agonist of retinoid X receptor that is approved for

Article Type:
Guideline
DOI:
https://doi.org/10.1159/000491388
Volume/Issue:
Volume 7: Issue 5
Free access