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Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China
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Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China
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, the cognitive deficits typically remain ( 7 ). Mounting evidence suggests that as one of the most extensively investigated regions in the brain, the hippocampus mediates cognitive functions, notably, learning, and memory functions. In both animals and
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] revealed reduced GMV in the hippocampus, parahippocampal gyrus, calcarine region, lingual gyrus and left temporal pole, and increased GMV in the supplementary motor area bilaterally. Again, no differences were seen for the cerebellum. Using metabolic
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11746232 21 Sui L, Li BM: Effects of perinatal hypothyroidism on regulation of reelin and brain-derived neurotrophic factor gene expression in rat hippocampus: role of DNA methylation and histone acetylation. Steroids 2010; 75: 988–997. 10.1016/j
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as well as in the hippocampus and striatum where it has been speculated to mediate neuronal T 3 uptake [ 37 ]. Moreover, Mct8 was also localized in choroid plexus structures and in brain capillary endothelial cells where it may participate in the
Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
Department of Clinical Chemistry, Endocrine Laboratory, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands
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Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam, The Netherlands
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Amsterdam Reproduction & Development Research Institute, Amsterdam, The Netherlands
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.1007/s00404-010-1362-z ) 4 Willoughby KA McAndrews MP Rovet JF . Effects of maternal hypothyroidism on offspring hippocampus and memory . Thyroid 2014 24 576 – 584 . ( https://doi.org/10.1089/thy.2013.0215 ) 5 Haddow JE Palomaki GE Allan
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, Pierozan P , Dos Santos K , et al. Reverse T 3 interacts with αvβ3 integrin receptor and restores enzyme activities in the hippocampus of hypothyroid developing rats: insight on signaling mechanisms . Mol Cell Endocrinol . 2018 Jul ; 470 : 281 – 94