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infarction, heart failure, and stroke are other common risk factors for AF ( 3 ). Today, the increased knowledge of the genetic causes of AF has revealed around 140 genetic loci associated with AF ( 4 ). Hyperthyroidism is also a common condition with an
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, 12 ). It is unsettled whether these pathophysiological observations can translate into an increased risk of non-thyroid cancer in patients with hyperthyroidism ( 13 ). Results from some ( 14 , 15 , 16 , 17 , 18 ), but not all ( 19 , 20 , 21
Department of Clinical Institute, Aalborg University, Aalborg, Denmark
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Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Institute, Aalborg University, Aalborg, Denmark
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Department of Clinical Institute, Aalborg University, Aalborg, Denmark
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Introduction Graves’ hyperthyroidism (GH) is an autoimmune disease mainly affecting the thyroid gland ( 1 , 2 ). The disease is usually transient with remission occurring within a period of 1–2 years after treatment with anti-thyroid drugs
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by thyroid disorders. This report describes a case of Graves hyperthyroidism after 8 years of tremelimumab therapy. We speculate a causal relationship between tremelimumab therapy and the development of Graves disease, and highlight the importance
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) is an effective blood purification procedure used to treat various disorders such as autoimmune diseases and familial hypercholesterolemia [ 2 ]. In hyperthyroidism, TPE has been used since 1970 [ 3 ] and is mainly considered for use in clinical
Department of Clinical Medicine, Aalborg University, Aalborg, Aarhus, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Aarhus, Denmark
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adverse outcome of pregnancy is less common than the early pregnancy loss but frequent enough to be of major concern [ 1 ]. Hyperthyroidism in women of reproductive age is most often caused by Graves' disease with autoimmunity against the thyroid
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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significant changes in tissue sensitivity to THs. Differently from RETH patients, who display hyperthyroid symptoms with increasing LT4 dose, our patients were euthyroid even in the presence of high FT4 levels with a normal TSH, similarly to what reported in
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it can persist causing hypothyroidism. A pathologic response to the exogenous iodine load may lead to iodine-induced hyperthyroidism (IIH), known as the Jod-Basedow phenomenon. IIH is infrequent, but elderly patients and individuals with autonomously
Department of Clinical Institute, Aalborg University, Aalborg, Denmark
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Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Introduction Hyperthyroidism is a common disease affecting women more often than men [ 1 ]. As first described by Parker et al. in 1961 [ 2 ], pregnancy is accompanied by a fall in thyroid antibody concentrations. Most [ 3 , 4 ], but not all
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Introduction Graves' disease (GD) is an autoimmune disease of the thyroid gland and is the most common cause of hyperthyroidism. The annual incidence is 20–50 cases per 100,000 people, with a peak incidence between the ages of 30 and 50. The