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Kaoru Kobayashi Kuma Hospital, Kobe City, Hyogo, Japan

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Mitsuyoshi Hirokawa Kuma Hospital, Kobe City, Hyogo, Japan

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Tomonori Yabuta Kuma Hospital, Kobe City, Hyogo, Japan

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Mitsuhiro Fukushima Kuma Hospital, Kobe City, Hyogo, Japan

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Minoru Kihara Kuma Hospital, Kobe City, Hyogo, Japan

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Yuuki Takamura Kuma Hospital, Kobe City, Hyogo, Japan

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Yasuhiro Ito Kuma Hospital, Kobe City, Hyogo, Japan

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Akihiro Miya Kuma Hospital, Kobe City, Hyogo, Japan

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Nobuyuki Amino Kuma Hospital, Kobe City, Hyogo, Japan

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Akira Miyauchi Kuma Hospital, Kobe City, Hyogo, Japan

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patients with honeycomb-like papillary thyroid carcinoma showing multiple small cysts, and describe the characteristic features on ultrasonography. Methods and Patients Ultrasonographic examination was performed by well-trained registered

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000353780
Volume/Issue:
Volume 2: Issue 4
Free access
Haggi Mazeh Department of Surgery, Jerusalem, Israel

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Amir Orlev Department of Surgery, Jerusalem, Israel

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Ido Mizrahi Department of Surgery, Jerusalem, Israel

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David J. Gross Endocrinology and Metabolism Service Hadassah-Hebrew University Medical Center, Jerusalem, Israel

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Herbert R. Freund Department of Surgery, Jerusalem, Israel

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Introduction Papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC) are both derived from the thyroid follicular cells. Of the two, PTC is the most common thyroid cancer, accounting for 75-80% of all thyroid

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000368750
Volume/Issue:
Volume 4: Issue 1
Free access
Daniela Cavaco Department of Endocrinology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Sara Carvalhal Department of General Surgery, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Valeriano Leite Department of Endocrinology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
NOVA Medical School/Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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life. Metastatic papillary thyroid carcinoma (PTC) with cutaneous metastases may cause pain, ulceration, and bleeding. Novel Insights ECT seems to be a safe and effective technique and may be an option for local palliative

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000507888
Volume/Issue:
Volume 9: Issue 4
Free access
Filipe Pereira Clinical and Experimental Endocrinology, Multidisciplinary Unit for Biomedical Research (UMIB), ICBAS, University of Porto, Porto

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Sofia S. Pereira Clinical and Experimental Endocrinology, Multidisciplinary Unit for Biomedical Research (UMIB), ICBAS, University of Porto, Porto
Instituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto

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Marta Mesquita Serviço de Anatomia Patológica, Instituto Português Oncologia de Lisboa, Francisco Gentil, Lisbon

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Tiago Morais Clinical and Experimental Endocrinology, Multidisciplinary Unit for Biomedical Research (UMIB), ICBAS, University of Porto, Porto

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Madalena M. Costa Clinical and Experimental Endocrinology, Multidisciplinary Unit for Biomedical Research (UMIB), ICBAS, University of Porto, Porto

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Pedro Quelhas Instituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto
Instituto de Engenharia Biomédica (INEB), Universidade do Porto, Porto

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Carlos Lopes Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP)
Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto

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Mariana P. Monteiro Clinical and Experimental Endocrinology, Multidisciplinary Unit for Biomedical Research (UMIB), ICBAS, University of Porto, Porto

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Valeriano Leite Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal
Serviço de Endocrinologia, Instituto Português de Oncologia de Lisboa, Francisco Gentil, Lisbon, Portugal

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Introduction Malignant thyroid tumors provide a good model to study the mechanisms underlying the metastatic process. The most prevalent thyroid tumors are papillary (PTC) and follicular (FTC) carcinomas. Although both originate from

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000457794
Volume/Issue:
Volume 6: Issue 2
Free access
Shinsuke Shinkai Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Kenji Ohba Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
Medical Education Center, Hamamatsu University School of Medicine, Shizuoka, Japan

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Kennichi Kakudo Department of Pathology and Thyroid Disease Center, Izumi City General Hospital, Osaka, Japan

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Takayuki Iwaki Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan

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Yoshihiro Mimura Department of Internal Medicine, American Hospital of Paris, Neuilly sur Seine, France

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Akio Matsushita Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Go Kuroda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Yuki Sakai Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Nobuhiko Nishino Department of Surgery, Maruyama Hospital, Shizuoka, Japan

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Kazuo Umemura Medical Education Center, Hamamatsu University School of Medicine, Shizuoka, Japan
Department of Pharmacology, Hamamatsu University School of Medicine, Shizuoka, Japan

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Takafumi Suda Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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Shigekazu Sasaki Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan

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common somatic mutation in papillary thyroid carcinoma). What Does This Case Report Add? • We identified concurrent BRAF mutation and TSHR polymorphism for the first time in a case of hyperfunctioning malignant thyroid nodule. • The findings

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000513552
Volume/Issue:
Volume 10: Issue 3
Free access
Sule Canberk Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal

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Joana C. Ferreira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Luísa Pereira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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Rui Batısta Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Andre F. Vieira Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal

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Paula Soares Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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Manuel Sobrinho Simões Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal
Abel Salazar Biomedical Sciences Institute (ICBAS), University of Porto, Porto, Portugal
Department of Pathology and Oncology, Centro Hospitalar São João, Porto, Portugal

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Valdemar Máximo Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Porto, Portugal
Department of Pathology, Faculty of Medicine of the University of Porto (FMUP), Porto, Portugal

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well-established driver mutations [ 1 , 2 ]. Papillary thyroid carcinoma (PTC), the most common type (i.e., 90% of all thyroid malignancies) probably contributes to most such tumours in this “dark zone” [ 3 ]. Approximately 90% of thyroid cancers

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000509183
Volume/Issue:
Volume 9: Issue 6
Free access
Hao Li Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otorhinolaryngology, Tan Tock Seng Hospital, Singapore, Singapore

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Nir Livneh Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Ramat Gan, Israel

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Snjezana Dogan Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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Ashok R. Shaha Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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Introduction Papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) are thyroid neoplasms derived from different cell types. While the former is common, the latter is much less frequent [ 1 , 2 ]. The synchronous occurrence

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000511184
Volume/Issue:
Volume 10: Issue 4
Free access
Pedro Marques Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal

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Valeriano Leite Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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Maria João Bugalho Endocrinology Department, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal
NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal

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Introduction Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. The widespread use of neck ultrasound (US) has led to the identification of small asymptomatic thyroid nodules with indeterminate clinical relevance [ 1

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000369133
Volume/Issue:
Volume 3: Issue 4
Free access
Inês Cosme Department of Endocrinology, Unidade Local de Saúde Santa Maria, Lisbon, Portugal

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Ana Figueiredo Department of Endocrinology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Sara Pinheiro Department of Endocrinology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Valeriano Leite Department of Endocrinology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal

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Introduction The incidence of thyroid carcinoma (TC) increased over the past 50 years ( 1 , 2 ) mainly due to a disproportionate increase in small papillary TC ( 3 ). In 2020, the GLOBOCAN database reported worldwide 586,000 cases of TC

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-24-0106
Volume/Issue:
Volume 13: Issue 4
Open access
Adile Begüm Bahçecioğlu Department of Endocrinology and Metabolism, Ankara University, School of Medicine, Ankara, Turkey

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Alptekin Gürsoy Department of Endocrinology and Metabolism, Ankara Guven Hospital, Ankara, Turkey

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Serpil Dizbay Sak Department of Pathology, Ankara University, School of Medicine Ankara, Turkey

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Seyfettin Ilgan Department of Nuclear Medicine, Ankara Guven Hospital, Ankara, Turkey

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Banu Bilezikçi Department of Pathology, Ankara Guven Hospital, Ankara, Turkey

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Murat Faik Erdoğan Department of Endocrinology and Metabolism, Ankara University, School of Medicine, Ankara, Turkey

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Introduction Ultrasonographic (US) echogenic microfoci (EMF) are frequently seen in papillary thyroid carcinoma (PTC). European Thyroid Association, the American College of Radiology (ACR), and the Korean Society of Thyroid Radiology classify

Article Type:
Research Article
Collections:
Thyroid cancer - clinical
DOI:
https://doi.org/10.1530/ETJ-23-0108
Volume/Issue:
Volume 12: Issue 6
Open access