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Junyu Tong
Junyu Tong
Department of Nuclear Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Maomei Ruan
Maomei Ruan
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
Department of Nuclear Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China
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Department of Nuclear Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China
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Yuchen Jin
Yuchen Jin
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Hao Fu
Hao Fu
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Lin Cheng
Lin Cheng
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Qiong Luo
Qiong Luo
Department of Nuclear Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China
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Zhiyan Liu
Zhiyan Liu
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
Department of Pathology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Department of Pathology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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Zhongwei Lv
Zhongwei Lv
Department of Nuclear Medicine, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China
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Libo Chen
Libo Chen
Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
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thyroid carcinoma derived from follicular epithelial cells, poorly differentiated thyroid carcinoma (PDTC) ranks between DTC and ATC regarding the degree of differentiation ( 4 ). PDTC was initially proposed as a separate entity by Sakamoto et al. in
João Roque
João Roque
Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar Universitário Lisboa Norte, Hospital de Santa Maria, Lisbon, Portugal
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Tiago Nunes Silva
Tiago Nunes Silva
Endocrinology, Diabetes and Metabolism Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
NOVA Medical School | Faculdade de Ciências Médicas of Universidade NOVA de Lisboa, Lisbon, Portugal
Unidade Investigação Patobiologia Molecular, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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NOVA Medical School | Faculdade de Ciências Médicas of Universidade NOVA de Lisboa, Lisbon, Portugal
Unidade Investigação Patobiologia Molecular, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Catarina Regala
Catarina Regala
Endocrinology, Diabetes and Metabolism Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Ricardo Rodrigues
Ricardo Rodrigues
Unidade Investigação Patobiologia Molecular, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Valeriano Leite
Valeriano Leite
Endocrinology, Diabetes and Metabolism Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
NOVA Medical School | Faculdade de Ciências Médicas of Universidade NOVA de Lisboa, Lisbon, Portugal
Unidade Investigação Patobiologia Molecular, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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NOVA Medical School | Faculdade de Ciências Médicas of Universidade NOVA de Lisboa, Lisbon, Portugal
Unidade Investigação Patobiologia Molecular, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Introduction The term poorly differentiated thyroid carcinoma (PDTC) was first introduced by Granner and colleagues in 1963, although it was only recognized as a distinct entity by the World Health Organization in 2004 ( 1 , 2 ). In 2006, the
Tiago Nunes da Silva
Tiago Nunes da Silva
Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Edward Limbert
Edward Limbert
Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Valeriano Leite
Valeriano Leite
Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Introduction Poorly differentiated thyroid carcinoma (PDTC) is a rare type of thyroid cancer accounting for < 6% of all thyroid malignancies [ 1 ]. Nevertheless, it is the second cause of death from follicular cell-derived thyroid cancer after
Lucie Allard
Lucie Allard
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Jérôme Alexandre Denis
Jérôme Alexandre Denis
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service de Biochimie Endocrinienne et Oncologique, UF Oncobiologie Cellulaire et Moléculaire, Pitié Salpêtrière, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Gaëlle Godiris Petit
Gaëlle Godiris Petit
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service de Chirurgie Générale, Viscérale et Endocrinienne, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Gabrielle Deniziaut
Gabrielle Deniziaut
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service d’Anatomo-Pathologie, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Cécile Ghander
Cécile Ghander
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Elise Mathy
Elise Mathy
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Erell Guillerm
Erell Guillerm
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, UF d’Onco-Angiogénétique et Génomique des Tumeurs Solides, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Charlotte Lussey-Lepoutre
Charlotte Lussey-Lepoutre
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Service de Médecine Nucléaire, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Laurence Leenhardt
Laurence Leenhardt
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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Camille Buffet
Camille Buffet
Sorbonne Université, GRC n°16, GRC Tumeurs Thyroïdiennes, Unité Thyroïde-Tumeurs Endocrines, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France
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compressive symptoms. The patient had refused surgery on a 6 cm-papillary thyroid carcinoma (PTC) diagnosed 3 years earlier. Initially, considering the size of the tumor, anaplastic or at least poorly differentiated carcinoma was suspected. Unexpectedly, but
Anne-Sophie Bertrand
Anne-Sophie Bertrand
Department of Interventional Radiology Imaging, Antoine Lacassagne Cancer Research Center, Nice, France
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Antoine Iannessi
Antoine Iannessi
Department of Interventional Radiology Imaging, Antoine Lacassagne Cancer Research Center, Nice, France
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Isabelle Peyrottes
Isabelle Peyrottes
Department of Anatomopathology, Antoine Lacassagne Cancer Research Center, Nice, France
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Alexis Lacout
Alexis Lacout
Department of Radiology, Centre médico-chirurgical ELSAN, Aurillac, France
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Antoine Thyss
Antoine Thyss
Department of Oncology, Antoine Lacassagne Cancer Research Center, Nice, France
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Pierre-Yves Marcy
Pierre-Yves Marcy
Department of Interventional Radiology and Diagnostic Imaging, Polyclinique Les Fleurs Groupe ELSAN, Ollioules, France
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case of tumor-to-tumor metastasis from a well-differentiated papillary thyroid carcinoma (PTC) into a benign uterine leiomyoma. Case Presentation We present the case of a 53-year-old female patient with a slow-growing latero-uterine mass on
Martina Tavarelli
Martina Tavarelli
Unité Thyroïde Tumeurs Endocrines, Paris, France
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Julie Sarfati
Julie Sarfati
Unité Thyroïde Tumeurs Endocrines, Paris, France
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Christian De Gennes
Christian De Gennes
Service de Médecine Interne Immuno-clinique, Paris, France
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Julien Haroche
Julien Haroche
Service de Médecine Interne 2, Paris, France
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Camille Buffet
Camille Buffet
Unité Thyroïde Tumeurs Endocrines, Paris, France
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Cécile Ghander
Cécile Ghander
Unité Thyroïde Tumeurs Endocrines, Paris, France
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Jean Marc Simon
Jean Marc Simon
Service de Radiothérapie, Paris, France
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Fabrice Ménégaux
Fabrice Ménégaux
Service de Chirurgie Générale et Digestive, Groupe Hospitalier et Faculté de Médecine Pitié-Salpêtrière, Institut du Cancer, Université Pierre et Marie Curie, Paris, France
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Laurence Leenhardt
Laurence Leenhardt
Unité Thyroïde Tumeurs Endocrines, Paris, France
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remove local tumoral tissue causing tracheal compression and dysphagia. This time, the histologic report found a poorly differentiated follicular thyroid cancer with extension to the periesophageal smooth muscle tissue classified as pT4NxMx. Then, 12
C. Mari Aparici
C. Mari Aparici
Nuclear Medicine, Radiology Department, University of California San Francisco, UCSF
Nuclear Medicine, Radiology Department, San Francisco VA Medical Center, San Francisco, Calif., USA
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Nuclear Medicine, Radiology Department, San Francisco VA Medical Center, San Francisco, Calif., USA
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T. Liu
T. Liu
Nuclear Medicine, Radiology Department, University of California San Francisco, UCSF
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consistent with postsurgical changes and residual disease. There was high FDG activity in multiple lung nodules and a single 1.2-cm right inguinal lymph node, with a maxSUV of 7. The findings were consistent with poorly differentiated papillary thyroid cancer
Dillwyn Williams
Dillwyn Williams
Department of Public Health, University of Cambridge, Cambridge, UK
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common; larger differentiated cancers and poorly differentiated and undifferentiated carcinomas are rare. Table 1 Proposed stages in the development of papillary thyroid carcinoma The chance of progression will be influenced by
Tim Brandenburg
Tim Brandenburg
Department of Endocrinology, Diabetes and Metabolism, Endocrine Tumour Center at West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Philipp Muchalla
Philipp Muchalla
Department of Endocrinology, Diabetes and Metabolism, Endocrine Tumour Center at West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Sarah Theurer
Sarah Theurer
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Kurt Werner Schmid
Kurt Werner Schmid
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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University Duisburg-Essen, Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Dagmar Führer
Dagmar Führer
Department of Endocrinology, Diabetes and Metabolism, Endocrine Tumour Center at West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Endocrine Tumour Center at West German Cancer Center, Member of ENDO-ERN and EURACAN, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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pathology revealed a poorly differentiated thyroid carcinoma. Additional workup including esophagogastroduodenoscopy (EGD) showed compression of the oesophagus but no oesophageal infiltration by the tumour. A percutaneous endoscopic gastrostomy tube was
Daniela Dias
Daniela Dias
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Inês Damásio
Inês Damásio
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Pedro Marques
Pedro Marques
Endocrinology Department, Hospital de Santa Maria, Centro Hospitalar Universitário de Lisboa Norte (CHULN), Lisbon, Portugal
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Helder Simões
Helder Simões
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Ricardo Rodrigues
Ricardo Rodrigues
Unidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Branca Maria Cavaco
Branca Maria Cavaco
Unidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
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Valeriano Leite
Valeriano Leite
Endocrinology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Unidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Nova Medical School: Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Lisbon, Portugal
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Unidade de Investigação em Patobiologia Molecular (UIPM), Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal
Nova Medical School: Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Lisbon, Portugal
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Bardet S & French TUTHYREF N etwork . Unusual short-term complete response to two regimens of cytotoxic chemotherapy in a patient with poorly differentiated thyroid carcinoma . Journal of Clinical Endocrinology and Metabolism 2012 97 3046 – 3050
