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Giorgio Radetti
Giorgio Radetti
Marienklinik, Bolzano, Italy
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Franco Rigon
Franco Rigon
Department of Paediatrics, University of Padua, Padua, Italy
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Alessandro Salvatoni
Alessandro Salvatoni
Department of Medicine and Surgery, University of Insubria, Varese, Italy
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Irene Campi
Irene Campi
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
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Tiziana De Filippis
Tiziana De Filippis
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
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Valentina Cirello
Valentina Cirello
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
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Silvia Longhi
Silvia Longhi
Department of Paediatrics, Regional Hospital of Bolzano, Bolzano, Italy
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Fabiana Guizzardi
Fabiana Guizzardi
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
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Marco Bonomi
Marco Bonomi
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Luca Persani
Luca Persani
Division of Endocrine and Metabolic Diseases and Laboratory of Endocrine and Metabolic Research, Istituto Auxologico Italiano, IRCCS, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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eutopic thyroid gland ( 1 ). The concomitant occurrence of CH and resistance to thyroid hormone syndrome type β (RTHβ) are exceptional, since only five patients have been described so far, and only in four patients, a mutation in the THRB gene has been
Yasmine Abdellaoui
Yasmine Abdellaoui
Department of Internal Medicine, Foch Hospital, Suresnes, France
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Dimitra Magkou
Dimitra Magkou
Department of Endocrinology and Nutrition, Ambroise Paré Universitary Hospital, Assistance Publique Hôpitaux de Paris, Boulogne, France
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Sofia Bakopoulou
Sofia Bakopoulou
Department of Endocrinology and Nutrition, Ambroise Paré Universitary Hospital, Assistance Publique Hôpitaux de Paris, Boulogne, France
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Ramona Zaharia
Ramona Zaharia
Department of Endocrinology and Nutrition, Ambroise Paré Universitary Hospital, Assistance Publique Hôpitaux de Paris, Boulogne, France
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Marie-Laure Raffin-Sanson
Marie-Laure Raffin-Sanson
Department of Endocrinology and Nutrition, Ambroise Paré Universitary Hospital, Assistance Publique Hôpitaux de Paris, Boulogne, France
EA 4340, Université Versailles Saint Quentin en Yvelines, UFR Simone Veil Santé, Montigny le Bretonneux, France
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EA 4340, Université Versailles Saint Quentin en Yvelines, UFR Simone Veil Santé, Montigny le Bretonneux, France
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Laure Cazabat
Laure Cazabat
Department of Endocrinology and Nutrition, Ambroise Paré Universitary Hospital, Assistance Publique Hôpitaux de Paris, Boulogne, France
EA 4340, Université Versailles Saint Quentin en Yvelines, UFR Simone Veil Santé, Montigny le Bretonneux, France
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EA 4340, Université Versailles Saint Quentin en Yvelines, UFR Simone Veil Santé, Montigny le Bretonneux, France
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contrasting with persistently elevated thyroid hormones during medical treatment of Graves’ disease may indicate RTHβ. Introduction Reduced sensitivity to thyroid hormone (TH) [ 1 ] is a rare disease with a prevalence of 1/40,000 [ 2 ]. It is
Genfeng Yu
Genfeng Yu
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Siyang Liu
Siyang Liu
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Cheng Song
Cheng Song
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Qintao Ma
Qintao Ma
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Xingying Chen
Xingying Chen
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Yuqi Jiang
Yuqi Jiang
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Hualin Duan
Hualin Duan
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Yajun He
Yajun He
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Dongmei Wang
Dongmei Wang
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Heng Wan
Heng Wan
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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Jie Shen
Jie Shen
Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Guangdong, China
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clarification. Given the inconsistent relationship between thyroid function and mortality, it is plausible to assume that these conflicting results are due to abnormal sensitivity to thyroid hormones in certain populations ( 18 ). Thyroid hormone sensitivity
Ying Sun
Ying Sun
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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Di Teng
Di Teng
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
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Lei Zhao
Lei Zhao
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China
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Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China
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Xiaoguang Shi
Xiaoguang Shi
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China
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Yongze Li
Yongze Li
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
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Zhongyan Shan
Zhongyan Shan
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
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Weiping Teng
Weiping Teng
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
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-Castillon P Cenarro A Civeira F . Impaired sensitivity to thyroid hormones is associated with diabetes and metabolic syndrome . Diabetes Care 2019 42 303 – 310 . ( https://doi.org/10.2337/dc18-1410 ) 2 Bowers J Terrien J Clerget-Froidevaux MS
Luca Persani
Luca Persani
Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milano, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
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Patrice Rodien
Patrice Rodien
Service d’Endocrinologie-Diabétologie-Nutrition, Centre de référence des maladies rares de la Thyroïde et des récepteurs hormonaux, CHU d’Angers, Angers, France.
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Carla Moran
Carla Moran
Institute of Metabolic Science, University of Cambridge, Cambridge, UK
Endocrine Section, Beacon Hospital, Dublin, Ireland.
School of Medicine, University College Dublin, Ireland
Endocrinology Department, St Vincent’s University Hospital, Dublin, Ireland
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Endocrine Section, Beacon Hospital, Dublin, Ireland.
School of Medicine, University College Dublin, Ireland
Endocrinology Department, St Vincent’s University Hospital, Dublin, Ireland
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W Edward Visser
W Edward Visser
Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
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Stefan Groeneweg
Stefan Groeneweg
Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
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Robin Peeters
Robin Peeters
Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
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Samuel Refetoff
Samuel Refetoff
Departments of Medicine and Paediatrics and Committee on Genetics, The University of Chicago, Chicago, Illinois, USA
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Mark Gurnell
Mark Gurnell
Institute of Metabolic Science, University of Cambridge, Cambridge, UK
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Paolo Beck-Peccoz
Paolo Beck-Peccoz
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milano, Italy
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Krishna Chatterjee
Krishna Chatterjee
Institute of Metabolic Science, University of Cambridge, Cambridge, UK
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definition of disorders with impaired sensitivity to thyroid hormones to include conditions with defective cellular uptake of TH via membrane transporters, reduced intracellular hormone metabolism generating T3 from T4, as well as resistance to thyroid
Jan Jiskra
Jan Jiskra
3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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Jiří Horáček
Jiří Horáček
4th Department of Medicine, Faculty of Medicine, Charles University, University Hospital Hradec Králové, Czech Republic
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Sylvie Špitálníková
Sylvie Špitálníková
Department of Nuclear Medicine, District Hospital, Havlíčkův Brod, Czech Republic
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Jan Paleček
Jan Paleček
3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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Zdeňka Límanová
Zdeňka Límanová
3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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Jan Krátký
Jan Krátký
3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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Drahomíra Springer
Drahomíra Springer
Department of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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Kristýna Žabková
Kristýna Žabková
3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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Hana Vítková
Hana Vítková
3rd Department of Medicine, 1st Faculty of Medicine, Charles University, General University Hospital, Prague, Czech Republic
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December 2009 in two iodine-sufficient areas of the Czech Republic – Prague ( n = 5520) and Vysočina region ( n = 2962). In total, 8482 women were examined for TSH (thyroid-stimulating hormone) and TPOAb (antibodies to thyroid peroxidase) in weeks 9–11 of
João Anselmo
João Anselmo
Department of Endocrinology and Nutrition, Hospital Divino Espírito Santo, Ponta Delgada, Portugal
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Carolina M. Chaves
Carolina M. Chaves
Department of Endocrinology and Nutrition, Hospital Divino Espírito Santo, Ponta Delgada, Portugal
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to affected mothers, we evaluated the sensitivity to TH with the use of a standard sensitive test that measures the TSH response to thyroid-releasing hormone (TRH) after the administration of the biologically active L-T 3 . The TSH response to TRH was
Tomohiro Kikuchi
Tomohiro Kikuchi
Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan
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Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan
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Shouhei Hanaoka
Shouhei Hanaoka
Department of Radiology, The University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
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Takahiro Nakao
Takahiro Nakao
Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
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Yukihiro Nomura
Yukihiro Nomura
Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage–ku, Chiba, Japan
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Center for Frontier Medical Engineering, Chiba University, Yayoicho, Inage–ku, Chiba, Japan
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Takeharu Yoshikawa
Takeharu Yoshikawa
Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
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Ashraful Alam
Ashraful Alam
Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
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Harushi Mori
Harushi Mori
Department of Radiology, Jichi Medical University, School of Medicine, Shimotsuke, Tochigi, Japan
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Naoto Hayashi
Naoto Hayashi
Department of Computational Diagnostic Radiology and Preventive Medicine, the University of Tokyo Hospital, Hongo, Bunkyo–ku, Tokyo, Japan
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study was to confirm the distribution of SUVs (mean SUV) in the normal population by thyroid function and comprehensively investigate whether mean SUV levels are related to thyroid hormone levels, age, sex, CT value, and thyroid volume. The probability
Till Ittermann
Till Ittermann
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Adrian Richter
Adrian Richter
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
German Rheumatism Research Center, Berlin, Germany
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German Rheumatism Research Center, Berlin, Germany
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Martin Junge
Martin Junge
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Matthias Nauck
Matthias Nauck
Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
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Astrid Petersmann
Astrid Petersmann
Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
Institute for Clinical Chemistry, Interdisciplinary University Laboratory, University Medicine Göttingen, Göttingen, Germany
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Institute for Clinical Chemistry, Interdisciplinary University Laboratory, University Medicine Göttingen, Göttingen, Germany
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Clemens Jürgens
Clemens Jürgens
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Harald Below
Harald Below
Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Greifswald, Germany
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Carsten Oliver Schmidt
Carsten Oliver Schmidt
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Henry Völzke
Henry Völzke
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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variations. For example, individual urinary iodine excretion levels vary strongly from day to day and during the day because they mainly depend on previous food intake [ 2 ]. Diurnal and seasonal variations have also been reported for thyroid hormone levels
Mehtap Cakir
Mehtap Cakir
Division of Endocrinology and Metabolism, Konya, Turkey
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Banu Turgut Ozturk
Banu Turgut Ozturk
Department of Ophthalmology, School of Medicine, Selcuk University, Konya, Turkey
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Elif Turan
Elif Turan
Division of Endocrinology and Metabolism, Konya, Turkey
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Gulsum Gonulalan
Gulsum Gonulalan
Division of Endocrinology and Metabolism, Konya, Turkey
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Ilker Polat
Ilker Polat
Departments of Internal Medicine, Konya, Turkey
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Kemal Gunduz
Kemal Gunduz
Departments of Ophthalmology, Meram School of Medicine, Konya Necmettin Erbakan University, Konya, Turkey
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.0128 20144040 21 Weiss AH, Kelly JP, Bisset D, Deeb SS: Reduced L- and M- and increased S-cone functions in an infant with thyroid hormone resistance due to mutations in the THRβ2 gene. Ophthalmic Genet 2012;33:187-195. 10
