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Introduction Thyroglobulin (Tg) is a thyroid-specific protein, and its serum levels are useful for monitoring patients with differentiated thyroid carcinomas (DTCs) who underwent total thyroidectomy. However, anti-Tg antibodies (TgAb) are
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UIC is highly influenced by recent iodine intake, it can only be used to determine iodine status for populations and not for individuals [ 9 ]. Serum thyroglobulin (Tg) may also be a suitable marker of the current iodine status in a population
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situation, with higher cutoffs suggested in non-thyroidectomized patients [ 16 ]. Moreover, one study suggests that positive serum anti-thyroglobulin antibodies (TgAb) lowered FNA-Tg levels and influenced the diagnostic accuracy of FNA-Tg in suspicious LNs
Thyroid Diseases Center, Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, Brazil
Fleury Medicina e Saúde, São Paulo, Brazil
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a nonsignificant risk of recurrence from undergoing unnecessary investigations and identify those individuals with a higher risk who merit closer follow-up [ 6 , 7 ]. The measurement of serum thyroglobulin (Tg) levels is one of the most important
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German Rheumatism Research Center, Berlin, Germany
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Institute for Clinical Chemistry, Interdisciplinary University Laboratory, University Medicine Göttingen, Göttingen, Germany
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agreement over the twelve visits, with mean differences of 0.09 mIU/L and 0.21 pmol/L and SDs of 0.06 mIU/L and 0.14 pmol/L, respectively. Very good agreements across the visits were observed for serum thyroglobulin level and thyroid volume. For the
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]. International guidelines [ 4 , 5 ] suggest a differentiation of patients into low and high risk, low risk patients having a life expectancy close to that of the background population. Serum thyroglobulin (s-Tg) is used as a tumor marker during follow-up after
Otorhinolaryngology, Tan Tock Seng Hospital, Singapore, Singapore
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Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Ramat Gan, Israel
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Endocrinol . 2010 ; 72 ( 4 ): 534 – 42 . http://dx.doi.org/10.1111/j.1365-2265.2009.03666.x . 25 Miyauchi A , Kudo T , Miya A , Kobayashi K , Ito Y , Takamura Y , . Prognostic impact of serum thyroglobulin doubling-time under
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L, Basolo F, Ugolini C, Pinchera A, Vitti P: Lymphocytic thyroiditis on histology correlates with serum thyroglobulin autoantibodies in patients with papillary thyroid carcinoma: impact on detection of serum thyroglobulin. J Clin Endocrinol Metab
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Introduction Differentiated thyroid cancer patients are monitored for local or distant recurrence after total thyroidectomy. They typically undergo physical examination, serial measurement of serum thyroglobulin (Tg) levels, and serial
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Department of Surgical, Medical and Molecular Pathology, Division of Thoracic Surgery, University of Pisa and University Hospital of Pisa, Pisa, Italy
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behaviour of serum anti-thyroglobulin autoantibodies (TgAbs) and anti-thyroperoxidase autoantibodies (TPOAbs) in relation to thymectomy over a 48-week follow-up period, with visits at 24 and 48 weeks. The secondary outcome was the relationship between TgAbs