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Laura Tosatto and Francesca Coscia

Introduction: thyroglobulin in thyroid hormone homeostasis The two thyroid hormones (TH) 3,5,3',5'-tetraiodo- l -thyronine (T4) and 3,3′,5-triiodo- l -thyronine (T3) are crucial for human metabolism and development ( 1 , 2 ). T4 is produced

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Bernadette L Dekker, Anouk N A van der Horst-Schrivers, Adrienne H Brouwers, Christopher M Shuford, Ido P Kema, Anneke C Muller Kobold, and Thera P Links

Introduction In the follow-up of patients with differentiated thyroid carcinoma (DTC), thyroglobulin (Tg) is a well-recognized tumor marker, and therefore, highly accurate Tg measurements are crucial ( 1 ). However, current immunoassays can

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Marta Amaro da Silveira Duval, André Borsatto Zanella, Ana Patrícia Cristo, Carlo Sasso Faccin, Marcia Silva Graudenz, and Ana Luiza Maia

cellularity or unsatisfying sampling precludes diagnosis in up to 20% of specimens, depending on the cytopathologist’s experience and skill [ 9 , 10 ]. Measurement of thyroglobulin in the washout of fine needle aspiration (FNA-Tg) has been used as an

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Eijun Nishihara, Nobuyuki Amino, Takumi Kudo, Kazuyoshi Kohsaka, Mitsuru Ito, Shuji Fukata, Mitsushige Nishikawa, Hirotoshi Nakamura, and Akira Miyauchi

, and positivity for thyroglobulin (Tg) hemagglutination antibodies and microsomal antibodies was tested [ 8 ]. However, the method was not sensitive enough to detect low levels of anti-thyroid antibodies. Therefore, earlier negative reports using Tg and

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Mathieu Spaas, Brigitte Decallonne, Annouschka Laenen, Jaak Billen, and Sandra Nuyts

normal thyroid tissue; secondly, RRA allows for serum thyroglobulin (Tg) to be used as a specific tumor marker and increases sensitivity of diagnostic whole-body iodine scintigraphy (WBS) in the follow-up, allowing early detection of recurrent or

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Yuan Li, Chenxu Zhao, Keli Zhao, Nan Yu, Yan Li, Yang Yu, Yang Zhang, Zhijing Song, Youyuan Huang, Guizhi Lu, Ying Gao, Junqing Zhang, and Xiaohui Guo

Introduction Thyroglobulin antibodies (TgAb), frequently found in healthy individuals, are serological markers of both Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) [ 1 ]. In papillary thyroid carcinoma (PTC), the rate of TgAb

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Stine Linding Andersen, Niels Henrik Bruun, Peter Astrup Christensen, Simon Lykkeboe, Aase Handberg, Annebirthe Bo Hansen, Maja Hjelm Lundgaard, Louise Knøsgaard, Nanna Maria Uldall Torp, Allan Carlé, Jesper Karmisholt, Inge Bülow Pedersen, Peter Vestergaard, and Stig Andersen

thyroglobulin antibodies (Tg-Ab) are the hallmarks of autoimmune hypothyroidism ( 3 ). Hypothyroidism is a concern in women who become pregnant, because of the association with adverse outcomes of pregnancy and child development ( 4 , 5 ). The adverse effects

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Cláudia C.D. Nakabashi, Teresa S. Kasamatsu, Felipe Crispim, Claudia A. Yamazaki, Cléber P. Camacho, Danielle M. Andreoni, Rosalia P. Padovani, Elza S. Ikejiri, Maria C.O.M. Mamone, Flávia C. Aldighieri, Jairo Wagner, Jairo T. Hidal, José G.H. Vieira, Rosa P.M. Biscolla, and Rui M.B. Maciel

a nonsignificant risk of recurrence from undergoing unnecessary investigations and identify those individuals with a higher risk who merit closer follow-up [ 6 , 7 ]. The measurement of serum thyroglobulin (Tg) levels is one of the most important

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Eijun Nishihara, Yoshitaka Hobo, Akira Miyauchi, Yasuhiro Ito, Miyoko Higuchi, Mitsuyoshi Hirokawa, Mitsuru Ito, Shuji Fukata, Mitsushige Nishikawa, and Takashi Akamizu

Introduction Thyroglobulin (Tg) is a thyroid-specific protein, and its serum levels are useful for monitoring patients with differentiated thyroid carcinomas (DTCs) who underwent total thyroidectomy. However, anti-Tg antibodies (TgAb) are

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Eftychia Koukkou, Ioannis Ilias, Irene Mamalis, Georgios G. Adonakis, and Kostas B. Markou

UIC is highly influenced by recent iodine intake, it can only be used to determine iodine status for populations and not for individuals [ 9 ]. Serum thyroglobulin (Tg) may also be a suitable marker of the current iodine status in a population