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Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Niels Henrik Bruun Unit of Clinical Biostatistics, Aalborg University Hospital, Aalborg, Denmark

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Peter Astrup Christensen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Simon Lykkeboe Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Aase Handberg Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Annebirthe Bo Hansen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Maja Hjelm Lundgaard Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Louise Knøsgaard Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Nanna Maria Uldall Torp Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Allan Carlé Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark

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Jesper Karmisholt Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark

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Inge Bülow Pedersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark

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Peter Vestergaard Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark

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Stig Andersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark

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Introduction Hypo- and hyperthyroidism in women of reproductive age are predominantly autoimmune disorders ( 1 , 2 ). Thyroid autoantibodies are key markers of underlying autoimmunity, and thyroid peroxidase antibodies (TPO-Ab) as well as

Article Type:
Research Article
Collections:
Thyroid and reproduction
DOI:
https://doi.org/10.1530/ETJ-22-0142
Volume/Issue:
Volume 11: Issue 6
Open access
Bing Han Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Chi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yi Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Ningjian Wang Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Jie Yu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Jing Cheng Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yingchao Chen Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Chunfang Zhu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yingli Lu Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China

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susceptibility and environmental factors [ 1 , 2 ]. Thyroid peroxidase antibody (TPOAb) concentrations are elevated in more than 90% patients with Hashimoto thyroiditis [ 3 , 4 ]. Furthermore, TPOAb is mostly related to heritability [ 5 ]. It was estimated that

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000506701
Volume/Issue:
Volume 10: Issue 1
Free access
Eijun Nishihara Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Nobuyuki Amino Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Takumi Kudo Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Kazuyoshi Kohsaka Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsuru Ito Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Shuji Fukata Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Mitsushige Nishikawa Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Hirotoshi Nakamura Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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Akira Miyauchi Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan

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/93. Native Tg and recombinant human TPO were used in all assay systems for the detection of TgAb and TPOAb, respectively. Table 1. Prevalence of thyroglobulin antibodies (TgAb) and thyroid peroxidase antibodies (TPOAb) in patients with subacute

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000501033
Volume/Issue:
Volume 8: Issue 5
Open access
Tumay Ozgur Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Hasan Gokce Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Ihsan Ustun Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Yaldiz Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Mehmet Mustafa Akin Departments of Pathology, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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Cumali Gokce Endocrinology and Metabolism, Mustafa Kemal University Medical Faculty, Hatay, Turkey

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.5–6.4 pmol/l), free T 4 12.87 (11.33–22.14 pmol/l), TSH 3.82 (0.63–4.82 mlU/l). Levels of thyroid antibodies consisting of thyroid peroxidase antibody (anti-TPO) were 600 (5–34 kU/l), and levels of the thyroglobulin antibodies (anti-TG) were 180.1 (0–60 kU

Article Type:
Case Report
DOI:
https://doi.org/10.1159/000342628
Volume/Issue:
Volume 1: Issue 3
Free access
Ying Sun Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

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Di Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Lei Zhao Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Laboratory Medicine, The First Affiliated Hospital of China Medical University, Heping District, Shenyang, Liaoning, China

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Xiaoguang Shi Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China
Department of Endocrinology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China

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Yongze Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Zhongyan Shan Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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Weiping Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, China

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high concentrations of thyroid peroxidase antibodies (TPOAb) and anti-thyroglobulin antibodies (TgAb), which may have a specific impact on thyroid function ( 7 ). Generally, the prevalence of thyroid disease is higher in women than in men ( 8 , 9

Article Type:
Research Article
Collections:
Environment and thyroid function
DOI:
https://doi.org/10.1530/ETJ-21-0084
Volume/Issue:
Volume 11: Issue 3
Open access
Marta Kostecka-Matyja Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Anna Fedorowicz Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Ewa Bar-Andziak Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Tomasz Bednarczuk Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Monika Buziak-Bereza Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Paulina Dumnicka Department of Medical Diagnostics, Jagiellonian University, Collegium Medicum, Krakow

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Maria Górska Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Bialystok

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Małgorzata Krasnodębska Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Beata Niedźwiedzka Department of Internal Medicine and Endocrinology, Medical University, Warsaw

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Dorota Pach Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan

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Katarzyna Siewko Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Bialystok

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Bogdan Solnica Department of Diagnostics, Chair of Clinical Biochemistry, Jagiellonian University, Collegium Medicum, Krakow, Poland

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Jerzy Sowiński Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan

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Małgorzata Szelachowska Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Bialystok

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Małgorzata Trofimiuk-Müldner Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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Katarzyna Wachowiak-Ochmańska Department of Endocrinology, Metabolism and Internal Medicine, University of Medical Sciences, Poznan

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Alicja Hubalewska-Dydejczyk Chair and Department of Endocrinology, Jagiellonian University, Collegium Medicum, Krakow

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-39). All women were healthy, had no history of thyroid disease, were using the recommended iodine prophylaxis, and had normal thyroid-peroxidase antibodies (anti-TPO <50 IU/mL). Anti-TPO was only measured as it is considered as a more sensitive marker of

Article Type:
Research Article
DOI:
https://doi.org/10.1159/000453061
Volume/Issue:
Volume 6: Issue 2
Free access
Jinrong Fu Department of Endocrinology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China
Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Zihao Fan Department of Geriatrics, Guangdong Provincial Geriatrics Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

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Liang He Department of Thyroid Surgery, The First Affiliated Hospital of China Medical University, Shenyang, China

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Qian Liu Department of Endocrinology and Metabolism, Jilin Cancer Hospital, Changchun, Jilin, China

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He Liu Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Yushu Li Department of Endocrinology and Metabolism, Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Affiliated Hospital of China Medical University, Shenyang, China

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Haixia Guan Department of Endocrinology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

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, including the accessibility of eligible participants during the study period and the feasibility of collecting data. Patients with elevated serum thyroid autoantibodies (thyroid peroxidase antibodies (TPOAb) >200 IU/mL and/or anti-thyroglobulin antibodies

Article Type:
Research Article
Collections:
Thyroid autoimmunity
DOI:
https://doi.org/10.1530/ETJ-23-0035
Volume/Issue:
Volume 12: Issue 5
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Chae Won Chung Department of Internal Medicine, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Korea
Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Korea

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Kyungsik Kim Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea

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Sue K Park Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea
Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Integrated Major in Innovative Medical Science, Seoul National University College of Medicine, Seoul, Korea

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Dal Lae Ju Department of Food Service and Nutrition Care, Seoul National University Hospital, Seoul, Korea

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Young Joo Park Department of Internal Medicine, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Korea
Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea

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Choong Ho Shin Department of Pediatrics, Seoul National University Children’s Hospital and Seoul National University College of Medicine, Seoul, Korea

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Jong Kwan Jun Department of Obstetrics and Gynecology, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Korea

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June-Key Chung Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

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Yoon Ju Song Department of Food Science and Nutrition, The Catholic University of Korea, Bucheon, Korea

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Young Ah Lee Department of Pediatrics, Seoul National University Children’s Hospital and Seoul National University College of Medicine, Seoul, Korea

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Gi Jeong Cheon Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea
Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea

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Sun Wook Cho Department of Internal Medicine, Seoul National University Hospital and Seoul National University College of Medicine, Seoul, Korea

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impact on anti-thyroid peroxidase antibody (anti-TPO Ab) and thyroid-stimulating hormone (TSH) levels in pregnant women ( 10 ). Additionally, the relationship between selenium deficiency and poor pregnancy outcomes also remains controversial. Several

Article Type:
Research Article
Collections:
Thyroid and reproduction
DOI:
https://doi.org/10.1530/ETJ-24-0007
Volume/Issue:
Volume 13: Issue 4
Open access
Liyuan Liu Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Yang Yu Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Lei Chen Department of Ultrasound, Peking University First Hospital, Beijing, People’s Republic of China

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Yang Zhang Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Guizhi Lu Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Ying Gao Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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Junqing Zhang Department of Endocrinology, Peking University First Hospital, Beijing, People’s Republic of China

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. Anti-Tg, antithyroglobulin antibody; anti-TPO, anti-thyroid peroxidase antibody. In terms of clinical manifestations, neck mass was the main clinical manifestation in both groups. Three patients in the PTL group even had compression symptoms

Article Type:
Research Article
Collections:
Thyroid autoimmunity
DOI:
https://doi.org/10.1530/ETJ-21-0144
Volume/Issue:
Volume 11: Issue 3
Open access
Louise Knøsgaard Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Stig Andersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark

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Annebirthe Bo Hansen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark

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Peter Vestergaard Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark

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Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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. Thyroid function and autoimmunity Serum residues from the blood samples were stored at −80°C until biochemical analyses of TSH, free T4 (fT4), thyroid peroxidase antibodies (TPO-Ab), and thyroglobulin antibodies (Tg-Ab). The analyses were performed in

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Research Article
Collections:
Thyroid and reproduction
DOI:
https://doi.org/10.1530/ETJ-21-0055
Volume/Issue:
Volume 11: Issue 2
Open access